Literature DB >> 31582008

Pharmacogenomics: Prescribing Precisely.

Dyson T Wake1, Nadim Ilbawi2, Henry Mark Dunnenberger1, Peter J Hulick3.   

Abstract

Pharmacogenomics (PGx) is a powerful tool that can predict increased risks of adverse effects and sub-therapeutic response to medications. This article establishes the core principles necessary for a primary care provider to meaningfully and prudently use PGx testing. Key topics include in which patients PGx testing should be considered, how PGx tests are ordered, how the results are translated into clinical recommendations, and what further advancements are likely in the near future. This will provide clinicians with a foundational knowledge of PGx that can allow incorporation of this tool into their practice or support further personal investigation.
Copyright © 2019 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Adverse effects; Medication optimization; Patient safety; Personalized medicine; Pharmacogenetic; Pharmacogenomic; Precision medicine

Mesh:

Year:  2019        PMID: 31582008     DOI: 10.1016/j.mcna.2019.07.002

Source DB:  PubMed          Journal:  Med Clin North Am        ISSN: 0025-7125            Impact factor:   5.456


  10 in total

Review 1.  Genetic polymorphisms associated with upper gastrointestinal bleeding: a systematic review.

Authors:  Marcela Forgerini; Rosa Camila Lucchetta; Gustavo Urbano; Tales Rubens de Nadai; Patrícia de Carvalho Mastroianni
Journal:  Pharmacogenomics J       Date:  2020-09-18       Impact factor: 3.550

2.  The Roles of Drug Metabolism-Related ADH1B in Immune Regulation and Therapeutic Response of Ovarian Cancer.

Authors:  Zhijie Xu; Bi Peng; Fanhua Kang; Wenqin Zhang; Muzhang Xiao; Jianbo Li; Qianhui Hong; Yuan Cai; Wei Liu; Yuanliang Yan; Jinwu Peng
Journal:  Front Cell Dev Biol       Date:  2022-06-09

Review 3.  Artificial Intelligence, Healthcare, Clinical Genomics, and Pharmacogenomics Approaches in Precision Medicine.

Authors:  Habiba Abdelhalim; Asude Berber; Mudassir Lodi; Rihi Jain; Achuth Nair; Anirudh Pappu; Kush Patel; Vignesh Venkat; Cynthia Venkatesan; Raghu Wable; Matthew Dinatale; Allyson Fu; Vikram Iyer; Ishan Kalove; Marc Kleyman; Joseph Koutsoutis; David Menna; Mayank Paliwal; Nishi Patel; Thirth Patel; Zara Rafique; Rothela Samadi; Roshan Varadhan; Shreyas Bolla; Sreya Vadapalli; Zeeshan Ahmed
Journal:  Front Genet       Date:  2022-07-06       Impact factor: 4.772

4.  "Pharmacogenetics of Cancer" - Cancer Drug Resistance special issue.

Authors:  Enrico Mini; Stefania Nobili
Journal:  Cancer Drug Resist       Date:  2020-02-20

5.  Realities of Pharmacogenomic and Minimizing Misconceptions and Medication Misadventures.

Authors:  Benjamin Duong
Journal:  Dela J Public Health       Date:  2021-12-15

Review 6.  Genophenotypic Factors and Pharmacogenomics in Adverse Drug Reactions.

Authors:  Ramón Cacabelos; Vinogran Naidoo; Lola Corzo; Natalia Cacabelos; Juan C Carril
Journal:  Int J Mol Sci       Date:  2021-12-10       Impact factor: 5.923

Review 7.  The Role of Pharmacogenomics in Opioid Prescribing.

Authors:  Aaron K Wong; Andrew A Somogyi; Justin Rubio; Jennifer Philip
Journal:  Curr Treat Options Oncol       Date:  2022-08-24

Review 8.  Organoid and microfluidics-based platforms for drug screening in COVID-19.

Authors:  Roya Ramezankhani; Roya Solhi; Yoke Chin Chai; Massoud Vosough; Catherine Verfaillie
Journal:  Drug Discov Today       Date:  2021-12-23       Impact factor: 8.369

Review 9.  Pharmacogenomics of genetic polymorphism within the genes responsible for SARS-CoV-2 susceptibility and the drug-metabolising genes used in treatment.

Authors:  Laith N Al-Eitan; Saif Z Alahmad
Journal:  Rev Med Virol       Date:  2020-11-17       Impact factor: 11.043

10.  Metabolomics reveals biomarkers in human urine and plasma to predict cytochrome P450 2D6 (CYP2D6) activity.

Authors:  Gaëlle Magliocco; Jules Desmeules; Alain Matthey; Luis M Quirós-Guerrero; Nasim Bararpour; Timothée Joye; Laurence Marcourt; Emerson F Queiroz; Jean-Luc Wolfender; Yvonne Gloor; Aurélien Thomas; Youssef Daali
Journal:  Br J Pharmacol       Date:  2021-09-09       Impact factor: 9.473

  10 in total

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