Min Yao1, Zhan-Ying Tang2, Xue-Jun Cui1, Yue-Li Sun1, Xiu-Lan Ye2, Ping Wang3, Wei-Hong Zhong4, Rui-Chun Zhang5, Hui-Ying Li6, Zhi-Jun Hu2, Wei-Min Wang3, Wei-Ping Qiao6, Jun Li2, Yang Gao2, Qi Shi1, Yong-Jun Wang1. 1. Institute of Spine Disease, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China. 2. Rehabilitation Department, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China. 3. Orthopaedics and Traumatology, First Teaching Hospital, Tianjin University of Traditional Chinese Medicine, Tianjin, China. 4. Rehabilitation Department, Rehabilitation Hospital, Fujian University of Traditional Chinese Medicine, Fuzhou, China. 5. Tuina Department, Xinjiang Uygur Autonomous Region Hospital of Traditional Chinese Medicine, Urumqi, China. 6. Orthopaedics and Traumatology, First Affiliated Hospital, Henan University of Traditional Chinese Medicine, Zhengzhou, China.
Abstract
Objectives: Large sample and high-quality evidence to evaluate the preliminary safety of the mobilizations and massage for cervical vertigo are not yet available. Thus, the present study aimed to investigate the comparative effectiveness and preliminary safety of Shi-style cervical mobilizations (SCM) compared with traditional massage (TM) in cervical vertigo patients. Design: A prospective, multicenter, open-label, randomized, controlled clinical trial with a 1:1 allocation ratio. Settings: Five academic medical centers. Subjects: A total of 360 adult patients with a diagnosis of cervical vertigo. Interventions: The patients were randomly allocated to either an SCM (n = 180) or TM (n = 180) group. The patients were treated during six sessions over 2 weeks. The primary outcome was the Dizziness Handicap Inventory (DHI) total scale score, and secondary outcomes included the DHI subscales, Chinese version of the Short-Form 36 Health Survey (CSF-36), and adverse events (AEs). Outcomes were assessed in the short term at 2 weeks, 1 month, and 3 months, and in the intermediate term at 6 months after randomization. Results: Significant changes were observed from the baseline in the DHI total scale and subscales at 2 weeks and 1, 3, and 6 months in both groups (all p < 0.05). However, the differences between the two groups were not significant (all p > 0.05). Furthermore, we noted significant changes from the baseline in SF-36 scores at 2 weeks in both groups (all p < 0.05), whereas CSF-36 scores were not significantly higher in the SCM group (all p > 0.05) compared with the TM group. No serious AEs were reported in either of the two groups. Conclusions: No differences in outcomes were detected between the SCM and TM groups in terms of treatment of cervicogenic dizziness. Efficacy trials are required to determine whether the improvement observed for each treatment was causally related to the interventions.
RCT Entities:
Objectives: Large sample and high-quality evidence to evaluate the preliminary safety of the mobilizations and massage for cervical vertigo are not yet available. Thus, the present study aimed to investigate the comparative effectiveness and preliminary safety of Shi-style cervical mobilizations (SCM) compared with traditional massage (TM) in cervical vertigopatients. Design: A prospective, multicenter, open-label, randomized, controlled clinical trial with a 1:1 allocation ratio. Settings: Five academic medical centers. Subjects: A total of 360 adult patients with a diagnosis of cervical vertigo. Interventions: The patients were randomly allocated to either an SCM (n = 180) or TM (n = 180) group. The patients were treated during six sessions over 2 weeks. The primary outcome was the Dizziness Handicap Inventory (DHI) total scale score, and secondary outcomes included the DHI subscales, Chinese version of the Short-Form 36 Health Survey (CSF-36), and adverse events (AEs). Outcomes were assessed in the short term at 2 weeks, 1 month, and 3 months, and in the intermediate term at 6 months after randomization. Results: Significant changes were observed from the baseline in the DHI total scale and subscales at 2 weeks and 1, 3, and 6 months in both groups (all p < 0.05). However, the differences between the two groups were not significant (all p > 0.05). Furthermore, we noted significant changes from the baseline in SF-36 scores at 2 weeks in both groups (all p < 0.05), whereas CSF-36 scores were not significantly higher in the SCM group (all p > 0.05) compared with the TM group. No serious AEs were reported in either of the two groups. Conclusions: No differences in outcomes were detected between the SCM and TM groups in terms of treatment of cervicogenic dizziness. Efficacy trials are required to determine whether the improvement observed for each treatment was causally related to the interventions.
Authors: Charlotte De Vestel; Luc Vereeck; Susan A Reid; Vincent Van Rompaey; Joris Lemmens; Willem De Hertogh Journal: J Man Manip Ther Date: 2022-04-06
Authors: Martha Funabashi; Lindsay M Gorrell; Katherine A Pohlman; Andrea Bergna; Nicola R Heneghan Journal: PLoS One Date: 2022-07-15 Impact factor: 3.752