Literature DB >> 31580152

Polyketides with quorum sensing inhibitory activity from the marine-derived fungus Aspergillus sp. ZF-79.

Fei Zhang1,2, Fan-Dong Kong2, Qing-Yun Ma2, Qing-Yi Xie2, Li-Man Zhou2, You-Xing Zhao2, Lei Guo1.   

Abstract

Seven compounds were isolated from a marine-derived fungus Aspergillus sp. ZF-79, including three new polyketides (1-3), named asperochrins D-F, along with four known compounds 4-7. Their structures were determined on the basis of spectroscopic methods. All the compounds were tested for quorum sensing inhibitory (QSI) activity. Compounds 1, 3, 4, 5, and 6 exhibited QSI activity against Chromobacterium violaceum CV026 with MIC values of 50, 100, 50, 50, and 6.25 μM, respectively.

Entities:  

Keywords:  sp.; polyketides; quorum sensing inhibitory activity

Year:  2019        PMID: 31580152     DOI: 10.1080/10286020.2019.1670647

Source DB:  PubMed          Journal:  J Asian Nat Prod Res        ISSN: 1028-6020            Impact factor:   1.569


  1 in total

1.  Altertoxins with Quorum Sensing Inhibitory Activities from The Marine-Derived Fungus Cladosporium sp. KFD33.

Authors:  Fei Zhang; Liman Zhou; Fandong Kong; Qingyun Ma; Qingyi Xie; Jiuhui Li; Haofu Dai; Lei Guo; Youxing Zhao
Journal:  Mar Drugs       Date:  2020-01-19       Impact factor: 5.118

  1 in total

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