| Literature DB >> 31577297 |
Fang Xu1, Qinwei Lu2, Po-Jung Jimmy Huang3, Juewen Liu3.
Abstract
We herein communicate the DNase I like activity of nanoceria (CeO2 nanoparticles). Both CeO2 and DNase I cleave polyadenine (poly-A) DNA down to ∼5-mer fragments as the major products, although further cleavage to even shorter fragments was observed with CeO2. Mass spectrometry indicates a hydrolytic cleavage mechanism instead of oxidative cleavage.Entities:
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Year: 2019 PMID: 31577297 DOI: 10.1039/c9cc06782e
Source DB: PubMed Journal: Chem Commun (Camb) ISSN: 1359-7345 Impact factor: 6.222