Literature DB >> 3157709

An evaluation of a 2% erythromycin ointment in the topical therapy of acne vulgaris.

J L Lesher, D K Chalker, J G Smith, L C Guenther, C N Ellis, J J Voorhees, A R Shalita, H C Klauda.   

Abstract

Two hundred eight patients completed a 12-week, multicenter, double-blind, controlled study comparing a 2% erythromycin ointment to its vehicle. Patients were evaluated by inflammatory lesion counts and Cook acne severity grade at the initial visit and at weeks 2, 4, 8, 10, and 12. The 2% erythromycin ointment proved to be statistically more effective than the vehicle in reducing lesion counts and acne severity grade at weeks 4, 8, 10, and 12. The ointment caused few side effects and was well tolerated by most patients.

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Year:  1985        PMID: 3157709     DOI: 10.1016/s0190-9622(85)70074-6

Source DB:  PubMed          Journal:  J Am Acad Dermatol        ISSN: 0190-9622            Impact factor:   11.527


  5 in total

Review 1.  Current views on the aetiology, pathogenesis and treatment of acne vulgaris.

Authors:  L Lever; R Marks
Journal:  Drugs       Date:  1990-05       Impact factor: 9.546

2.  Influence of topical erythromycin preparations for acne vulgaris on skin surface pH.

Authors:  H C Korting; M Kerscher; M Schäfer-Korting; U Berchtenbreiter
Journal:  Clin Investig       Date:  1993-08

Review 3.  Acne vulgaris.

Authors:  Sarah Purdy; David Deberker
Journal:  BMJ Clin Evid       Date:  2008-05-15

Review 4.  Transdermal penetration of topical drugs used in the treatment of acne.

Authors:  Andrea Krautheim; Harald Gollnick
Journal:  Clin Pharmacokinet       Date:  2003       Impact factor: 6.447

Review 5.  Acne vulgaris.

Authors:  Sarah Purdy; David de Berker
Journal:  BMJ Clin Evid       Date:  2011-01-05
  5 in total

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