Literature DB >> 31576854

LAMP-generated H+ ions-induced dimer i-motif as signal transducer for ultrasensitive electrochemical detection of DNA.

Xiaoyu Hua1, Enfen Yang1, Wenting Yang1, Ruo Yuan1, Wenju Xu1.   

Abstract

Herein, an ultrasensitive electrochemical biosensor is proposed for the quantification of the Flu A virus biomarker DNA (fDNA), and is based on loop-mediated isothermal amplification-generated hydrogen ions (LAMP-H+) which induce the formation of the dimer i-motif structure (DiMS) for signal transduction, coupled with exonuclease III (ExoIII)-assisted DNA walking for signal dual-amplification.

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Year:  2019        PMID： 31576854     DOI： 10.1039/c9cc06738h

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  3 in total

1.  Rational design of guiding elements to control folding topology in i-motifs with multiple quadruplexes.

Authors:  Alexander S Minasyan; Srinivas Chakravarthy; Suchitra Vardelly; Mark Joseph; Evgueni E Nesterov; Irina V Nesterova
Journal:  Nanoscale       Date:  2021-05-20       Impact factor: 7.790

2.  Towards a versatile and economic Chagas Disease point-of-care testing system, by integrating loop-mediated isothermal amplification and contactless/label-free conductivity detection.

Authors:  Federico Figueredo; Fabiana Stolowicz; Adrián Vojnov; Wendell K T Coltro; Luciana Larocca; Carolina Carrillo; Eduardo Cortón
Journal:  PLoS Negl Trop Dis       Date:  2021-05-14

3.  Electrochemical Detection for Isothermal Loop-Mediated Amplification of Pneumolysin Gene of Streptococcus pneumoniae Based on the Oxidation of Phenol Red Indicator.

Authors:  Andrea González-López; María Dolores Cima-Cabal; Pablo Rioboó-Legaspi; Estefanía Costa-Rama; María Del Mar García-Suárez; M Teresa Fernández-Abedul
Journal:  Anal Chem       Date:  2022-09-15       Impact factor: 8.008
  3 in total

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