Literature DB >> 3157346

Effectiveness of aztreonam for the treatment of gonorrhea.

A Gottlieb, J Mills.   

Abstract

Aztreonam, 1 g intramuscularly, was compared with spectinomycin, 2 g intramuscularly, for uncomplicated gonorrhea. There were no failures with either drug. For aztreonam, there were 26 urethral, 3 rectal, and 3 endocervical sites that were infected. Aztreonam in a single dose of 1 g intramuscularly is satisfactory therapy for uncomplicated urethral gonorrhea in men and may be effective for rectal and endocervical infection as well.

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Year:  1985        PMID： 3157346      PMCID： PMC176252          DOI： 10.1128/AAC.27.2.270

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  7 in total

1.  Monobactams--structure-activity relationships leading to SQ 26,776.

Authors:  H Breuer; C M Cimarusti; T Denzel; W H Koster; W A Slusarchyk; U D Treuner
Journal:  J Antimicrob Chemother       Date:  1981-12       Impact factor: 5.790

2.  In vitro activity and beta-lactamase stability of a monobactam, SQ 26,917, compared with those of aztreonam and other agents.

Authors:  H C Neu; P Labthavikul
Journal:  Antimicrob Agents Chemother       Date:  1983-08       Impact factor: 5.191

3.  Sch 29482--a novel penem antibiotic: an in-vitro comparison of its activity with other beta-lactams.

Authors:  R M Brown; R Wise; J M Andrews
Journal:  J Antimicrob Chemother       Date:  1982-02       Impact factor: 5.790

4.  Comparative in vitro study of SQ26,776.

Authors:  V Fainstein; S Weaver; G P Bodey
Journal:  Antimicrob Agents Chemother       Date:  1982-02       Impact factor: 5.191

5.  Review of single- and multiple-dose pharmacokinetics of the monobactam, aztreonam (SQ 26,776) in healthy subjects.

Authors:  E A Swabb; A A Sugerman
Journal:  Chemotherapy       Date:  1983       Impact factor: 2.544

6.  Effectiveness of aztreonam, a new monobactam antibiotic, against penicillin-resistant gonococci.

Authors:  L K Miller; P L Sanchez; S W Berg; S B Kerbs; W O Harrison
Journal:  J Infect Dis       Date:  1983-09       Impact factor: 5.226

7.  In vitro activity of azthreonam, a monobactam antibiotic.

Authors:  N V Jacobus; M C Ferreira; M Barza
Journal:  Antimicrob Agents Chemother       Date:  1982-11       Impact factor: 5.191
  7 in total
  3 in total

1.  Treatment of uncomplicated gonorrhoea with single dose aztreonam.

Authors:  D T Evans; A J Crooks; C Jones; R A Holman; S W Price
Journal:  Genitourin Med       Date:  1986-10

2.  Aztreonam for Neisseria gonorrhoeae: a systematic review and meta-analysis.

Authors:  Lindley A Barbee; Matthew R Golden
Journal:  J Antimicrob Chemother       Date:  2020-07-01       Impact factor: 5.790

Review 3.  Aztreonam. A review of its antibacterial activity, pharmacokinetic properties and therapeutic use.

Authors:  R N Brogden; R C Heel
Journal:  Drugs       Date:  1986-02       Impact factor: 9.546
  3 in total

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