| Literature DB >> 31568974 |
Gustavo H G Matsushita1, Adam H Sugi2, Yandre M G Costa3, Alexander Gomez-A4, Claudio Da Cunha2, Luiz S Oliveira5.
Abstract
Dopamine has a major behavioral impact related to drug dependence, learning and memory functions, as well as pathologies such as schizophrenia and Parkinson's disease. Phasic release of dopamine can be measured in vivo with fast-scan cyclic voltammetry. However, even for a specialist, manual analysis of experiment results is a repetitive and time consuming task. This work aims to improve the automatic dopamine identification from fast-scan cyclic voltammetry data using convolutional neural networks (CNN). The best performance obtained in the experiments achieved an accuracy of 98.31% using a combined CNN approach. The end-to-end object detection system using YOLOv3 achieved an accuracy of 97.66%. Also, a new public dopamine release dataset was presented, and it is available at https://web.inf.ufpr.br/vri/databases/phasicdopaminerelease/.Entities:
Keywords: Convolutional neural network; Fast-scan cyclic voltammetry; Machine learning; Pattern recognition; Phasic dopamine release; YOLO
Year: 2019 PMID: 31568974 DOI: 10.1016/j.compbiomed.2019.103466
Source DB: PubMed Journal: Comput Biol Med ISSN: 0010-4825 Impact factor: 4.589