Inadvertent Massive Overdose of Lidocaine in an Infant With Arthrogryposis Multiplex Congenita Treated Successfully With Lipid Emulsion.

Severe local anesthetic toxicity is potentially life threatening and is often refractory to standard resuscitative measures. Infants are a particularly susceptible population in this regard because of their unique physiologic features. Recently, 20% intravenous (IV) lipid emulsion (Intralipid) has been proposed as a "one-stop solution" to toxicity related to all commonly used amide local anesthetics. There is an abundance of literature describing its uses in association with regional blocks in adults. However, there is a scarcity of reports describing its application in children, and use of 10% IV lipid emulsion (Intralipid) has not been described in children for rescue therapy, to our knowledge. We report a case of accidental life-threatening overdose of IV lidocaine (lignocaine) in an infant, which was successfully managed with 10% lipid emulsion. Copyright© by the American Association of Nurse Anesthetists.