Literature DB >> 3156590

Relationship between membrane-bound protein kinase C activity and calcium-dependent proliferation of BALB/c 3T3 cells.

T E Donnelly, R Sittler, E M Scholar.   

Abstract

Extracellular calcium-deprivation inhibited the proliferation of BALB/c 3T3 cells and this inhibition correlated with a loss of protein kinase C activity from the particulate fraction. Addition of calcium induced proliferation of the cells with the DNA synthetic activity returning to the control rate at 18 hours following calcium addition. The level of protein kinase C activity in the particulate fraction was monitored at various times after calcium addition and increased in parallel with the DNA synthetic activity.

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Year:  1985        PMID: 3156590     DOI: 10.1016/0006-291x(85)90247-5

Source DB:  PubMed          Journal:  Biochem Biophys Res Commun        ISSN: 0006-291X            Impact factor:   3.575


  2 in total

Review 1.  Calcium, cyclic AMP and protein kinase C--partners in mitogenesis.

Authors:  J F Whitfield; J P Durkin; D J Franks; L P Kleine; L Raptis; R H Rixon; M Sikorska; P R Walker
Journal:  Cancer Metastasis Rev       Date:  1987       Impact factor: 9.264

2.  Effect of hexadecane on protein kinase C of pig epidermis.

Authors:  H Koizumi; K Yamanaka; A Ohkawara
Journal:  Arch Dermatol Res       Date:  1987       Impact factor: 3.017

  2 in total

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