Optimal Management of High-risk Stage I Nonseminoma Germ Cell Tumor: Active Intervention is the Preferred Option.

While there is still debate and uncertainty regarding the best management strategy for clinical stage IB nonseminoma germ cell tumor, adjuvant treatment with chemotherapy or surgery is associated with a markedly lower risk of recurrence for men with high-risk features and provides more definitive disease control and lower overall exposure to chemotherapy for patients who do experience recurrence.