Literature DB >> 31564639

Acne: Transient Arrest in the Homeostatic Host-Microbiota Dialog?

Andrea Szegedi1, Zsolt Dajnoki2, Tamás Bíró3, Lajos Kemény4, Dániel Törőcsik2.   

Abstract

We propose that acne vulgaris represents a naturally developing, transient inflammatory interaction of adolescent facial skin with its new microbial/chemical milieu (Cutibacterium acnes, sebum), replacing a state of previous childhood skin homeostasis. This concept might explain why acne is characterized by strong regional and age specificity, prevalent occurrence, and resolution.
Copyright © 2019 The Authors. Published by Elsevier Ltd.. All rights reserved.

Entities:  

Keywords:  Cutibacterium acnes; acne; homeostasis; inflammation; microbiota; sebum

Year:  2019        PMID: 31564639     DOI: 10.1016/j.it.2019.08.006

Source DB:  PubMed          Journal:  Trends Immunol        ISSN: 1471-4906            Impact factor:   16.687


  5 in total

Review 1.  The Skin Microbiome in Cutaneous T-Cell Lymphomas (CTCL)-A Narrative Review.

Authors:  Magdalena Łyko; Alina Jankowska-Konsur
Journal:  Pathogens       Date:  2022-08-18

Review 2.  Potential roles of gut microbial tryptophan metabolites in the complex pathogenesis of acne vulgaris.

Authors:  Yukun Huang; Lu Liu; Zhenyu Hao; Lingna Chen; Qian Yang; Xia Xiong; Yongqiong Deng
Journal:  Front Microbiol       Date:  2022-07-27       Impact factor: 6.064

3.  Epidermal Barrier Integrity is Associated with Both Skin Microbiome Diversity and Composition in Patients with Acne Vulgaris.

Authors:  Xia Xiong; Jingdong Lai; Lin Zhou; Xueping Liu; Xulin Li; Xiangyan He
Journal:  Clin Cosmet Investig Dermatol       Date:  2022-09-28

4.  Tumour Necrosis Factor Alpha-induced Protein 3 Negatively Regulates Cutibacterium acnes-induced Innate Immune Events in Epidermal Keratinocytes.

Authors:  Lilla Erdei; Beáta Szilvia Bolla; Renáta Bozó; Gábor Tax; Edit Urbán; Katalin Burián; Lajos Kemény; Kornélia Szabó
Journal:  Acta Derm Venereol       Date:  2021-01-13       Impact factor: 3.875

Review 5.  Applications of Human Skin Microbiota in the Cutaneous Disorders for Ecology-Based Therapy.

Authors:  Hong Zhou; Linlin Shi; Yuanyuan Ren; Xi Tan; Wei Liu; Zhi Liu
Journal:  Front Cell Infect Microbiol       Date:  2020-10-22       Impact factor: 5.293

  5 in total

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