Kenneth M Langa1,2,3,4, Lindsay H Ryan5, Ryan J McCammon5, Richard N Jones6, Jennifer J Manly7, Deborah A Levine8,9,10, Amanda Sonnega5, Madeline Farron8, David R Weir5. 1. Division of General Medicine, Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, Michigan, USA, klanga@umich.edu. 2. Veterans Affairs Center for Clinical Management Research, Ann Arbor, Michigan, USA, klanga@umich.edu. 3. Institute for Social Research, University of Michigan, Ann Arbor, Michigan, USA, klanga@umich.edu. 4. Institute for Healthcare Policy and Innovation, University of Michigan, Ann Arbor, Michigan, USA, klanga@umich.edu. 5. Institute for Social Research, University of Michigan, Ann Arbor, Michigan, USA. 6. Department of Psychiatry and Human Behavior and Neurology, Brown University Warren Alpert Medical School, Providence, Rhode Island, USA. 7. Columbia University Gertrude H. Sergievsky Center, Taub Institute for Research in Aging and Alzheimer's disease, New York, New York, USA. 8. Division of General Medicine, Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, Michigan, USA. 9. Institute for Healthcare Policy and Innovation, University of Michigan, Ann Arbor, Michigan, USA. 10. Department of Neurology and Stroke Program, University of Michigan, Ann Arbor, Michigan, USA.
Abstract
INTRODUCTION: The Harmonized Cognitive Assessment Protocol (HCAP) Project is a substudy within the Health and Retirement Study (HRS), an ongoing nationally representative panel study of about 20,000 adults aged 51 or older in the United States. The HCAP is part of an international research collaboration funded by the National Institute on Aging to better measure and identify cognitive impairment and dementia in representative population-based samples of older adults, in the context of ongoing longitudinal studies of aging in high-, middle-, and low-income countries around the world. METHODS: The HCAP cognitive test battery was designed to measure a range of key cognitive domains affected by cognitive aging (including attention, memory, executive function, language, and visuospatial function) and to allow harmonization and comparisons to other studies in the United States and around the world. The HCAP included a pair of in-person interviews, one with the target HRS respondent (a randomly selected HRS sample member, aged 65+) that lasted approximately 1 h and one with an informant nominated by the respondent that lasted approximately 20 min. The final HRS HCAP sample included 3,496 study subjects, representing a 79% response rate among those invited to participate. CONCLUSION: Linking detailed HCAP cognitive assessments to the wealth of available longitudinal HRS data on cognition, health, biomarkers, genetics, health care utilization, informal care, and economic resources and behavior will provide unique and expanded opportunities to study cognitive impairment and dementia in a nationally representative US population-based sample. The fielding of similar HCAP projects in multiple countries around the world will provide additional opportunities to study international differences in the prevalence, incidence, and outcomes of dementia globally with comparable data. Like all HRS data, HCAP data are publicly available at no cost to researchers.
INTRODUCTION: The Harmonized Cognitive Assessment Protocol (HCAP) Project is a substudy within the Health and Retirement Study (HRS), an ongoing nationally representative panel study of about 20,000 adults aged 51 or older in the United States. The HCAP is part of an international research collaboration funded by the National Institute on Aging to better measure and identify cognitive impairment and dementia in representative population-based samples of older adults, in the context of ongoing longitudinal studies of aging in high-, middle-, and low-income countries around the world. METHODS: The HCAP cognitive test battery was designed to measure a range of key cognitive domains affected by cognitive aging (including attention, memory, executive function, language, and visuospatial function) and to allow harmonization and comparisons to other studies in the United States and around the world. The HCAP included a pair of in-person interviews, one with the target HRS respondent (a randomly selected HRS sample member, aged 65+) that lasted approximately 1 h and one with an informant nominated by the respondent that lasted approximately 20 min. The final HRS HCAP sample included 3,496 study subjects, representing a 79% response rate among those invited to participate. CONCLUSION: Linking detailed HCAP cognitive assessments to the wealth of available longitudinal HRS data on cognition, health, biomarkers, genetics, health care utilization, informal care, and economic resources and behavior will provide unique and expanded opportunities to study cognitive impairment and dementia in a nationally representative US population-based sample. The fielding of similar HCAP projects in multiple countries around the world will provide additional opportunities to study international differences in the prevalence, incidence, and outcomes of dementia globally with comparable data. Like all HRS data, HCAP data are publicly available at no cost to researchers.
Authors: Brenda L Plassman; Kenneth M Langa; Ryan J McCammon; Gwenith G Fisher; Guy G Potter; James R Burke; David C Steffens; Norman L Foster; Bruno Giordani; Frederick W Unverzagt; Kathleen A Welsh-Bohmer; Steven G Heeringa; David R Weir; Robert B Wallace Journal: Ann Neurol Date: 2011-03-18 Impact factor: 10.422
Authors: Lauren H Nicholas; Julie P W Bynum; Theodore J Iwashyna; David R Weir; Kenneth M Langa Journal: Health Aff (Millwood) Date: 2014-04 Impact factor: 6.301
Authors: David J Llewellyn; Iain A Lang; Fiona E Matthews; Brenda L Plassman; Mary Am Rogers; Lewis B Morgenstern; Gwenith G Fisher; Mohammed U Kabeto; Kenneth M Langa Journal: Alzheimers Res Ther Date: 2010-06-24 Impact factor: 6.982
Authors: Michael D Hurd; Paco Martorell; Adeline Delavande; Kathleen J Mullen; Kenneth M Langa Journal: N Engl J Med Date: 2013-04-04 Impact factor: 91.245
Authors: B L Plassman; K M Langa; G G Fisher; S G Heeringa; D R Weir; M B Ofstedal; J R Burke; M D Hurd; G G Potter; W L Rodgers; D C Steffens; R J Willis; R B Wallace Journal: Neuroepidemiology Date: 2007-10-29 Impact factor: 3.282
Authors: Kathryn N Devlin; Laura Brennan; Laura Saad; Tania Giovannetti; Roy H Hamilton; David A Wolk; Sharon X Xie; Dawn Mechanic-Hamilton Journal: J Alzheimers Dis Date: 2022 Impact factor: 4.472
Authors: Jinkook Lee; Pranali Y Khobragade; Joyita Banerjee; Sandy Chien; Marco Angrisani; Arokiasamy Perianayagam; David E Bloom; Aparajit B Dey Journal: J Am Geriatr Soc Date: 2020-08 Impact factor: 5.562
Authors: Madeline R Farron; Mohammed U Kabeto; Aparajit Ballav Dey; Joyita Banerjee; Deborah A Levine; Kenneth M Langa Journal: J Am Geriatr Soc Date: 2020-08 Impact factor: 5.562