Literature DB >> 31563751

Clinical outcomes of intracranial complications secondary to acute mastoiditis: The Alder Hey experience.

Madhan Krishnan1, Hussein Walijee2, Anthony Jesurasa3, Su De2, Ajay Sinha3, Ravi Sharma2, Adam Donne2.   

Abstract

OBJECTIVE: Acute mastoiditis is the most common intra-temporal complication of acute otitis media. Its management remains a challenge due to potential extracranial and intracranial complications. This study was designed to evaluate the recent experience with acute mastoiditis and its associated intracranial complications at a tertiary paediatric centre.
METHODS: A retrospective case note review was carried out for patients admitted to Alder Hey Children's Hospital between January 2006 and December 2016 with a diagnosis of acute mastoiditis. Patients were identified using ICD-10 codes H700, H701, H702, H708 and H709. A case note review was performed to identify patients with intracranial complications and data collected.
RESULTS: 30 patients were identified with intracranial complications of acute mastoiditis, with 18 males and 12 females. The average age was 4 years and 2 months (range 2 months-15 years). The most common presenting complaint was otalgia and vomiting (63%), with only 27% patients presenting with mastoid swelling. 83% of patients were investigated with a combination of CT and MRI scans, 6.7% with CT scans only and 6.7% with MRI scans only. 73% were diagnosed with sinus thrombosis, 40% cerebral abscess and 33% postauricular subperiosteal abscess. 78% of the patients required surgical intervention. 27 of the 30 patients recovered fully with no significant long term sequalae following an average of 50 months follow-up.
CONCLUSION: Intracranial complications of acute mastoiditis remain a significant challenge. Most patients tend to present without mastoid swelling, necessitating a high index of suspicion in patients with picket fence fever, vomiting, drowsiness, headaches, seizures or cranial nerve involvement. Most cases treated at our institution required acute surgical intervention in addition to adjuvant medical treatment with majority patients recovering fully. Crown
Copyright © 2019. Published by Elsevier B.V. All rights reserved.

Entities:  

Keywords:  Abscess; Intracranial complications; Mastoiditis; Otitis media; Sinus thrombosis

Mesh:

Year:  2019        PMID: 31563751     DOI: 10.1016/j.ijporl.2019.109675

Source DB:  PubMed          Journal:  Int J Pediatr Otorhinolaryngol        ISSN: 0165-5876            Impact factor:   1.675


  4 in total

1.  Ventriculitis Presenting as a Complication of Haemophilus Influenzae Mastoiditis and Meningitis.

Authors:  Amy Kiamos; Swetha R Nuthulaganti; Rahul Gujarathi; Narsimha Candula
Journal:  Cureus       Date:  2022-04-25

2.  Role of Surfactant Protein D in Experimental Otitis Media.

Authors:  Osama Abdel-Razek; Tianyi Liu; Xinghua Chen; Qiushi Wang; Gautam Vanga; Guirong Wang
Journal:  J Innate Immun       Date:  2021-02-08       Impact factor: 7.349

3.  Niche- and Gender-Dependent Immune Reactions in Relation to the Microbiota Profile in Pediatric Patients with Otitis Media with Effusion.

Authors:  Frida Enoksson; Alicia Ruiz Rodriguez; Chikondi Peno; Carlos Balcazar Lopez; Fredrik Tjernström; Debby Bogaert; Anders P Hakansson; Caroline Bergenfelz
Journal:  Infect Immun       Date:  2020-09-18       Impact factor: 3.441

4.  The risk factors of intracranial infection in patients with intracerebral hemorrhage undergone hematoma puncture: what should we care.

Authors:  Haijing Han; Yu Li; Li Liu; Ningning Liu; Ying Wang; Min Zhang
Journal:  BMC Infect Dis       Date:  2020-12-11       Impact factor: 3.090

  4 in total

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