Zhe Wu Jin1, Kwang Ho Cho2, Dong Yuan Xu3, Ya Qian You4, Ji Hyun Kim5, Gen Murakami6, Hiroshi Abe7. 1. Department of Anatomy, Wuxi Medical School, Jiangnan University, Wuxi, China. Electronic address: kimchero@hanmail.net. 2. Department of Neurology, Wonkwang University School of Medicine and Hospital, Institute of Wonkwang Medical Science, 895, Muwang-ro, Iksan-si, Jeollabuk-do, 54538, Republic of Korea. Electronic address: neurlogy@wonkwang.ac.kr. 3. Center of Morphological Experiment, Medical College of Yanbian University, Yanji, 133002, China. Electronic address: dyxu@ybu.edu.cn. 4. Department of Anatomy, Wuxi Medical School, Jiangnan University, Wuxi, China. Electronic address: yqyjiangnan@163.com. 5. Department of Anatomy, Chonbuk University School of Medicine, Jeonju, Republic of Korea. Electronic address: 407kk@hanmail.net. 6. Division of Internal Medicine, Jikou-kai Clinic for Home Visit, Japan. Electronic address: g.murakami@asuka-gp.or.jp. 7. Department of Anatomy, Akita University School of Medicine, Akita, Japan. Electronic address: abe@med.akita-u.ac.jp.
Abstract
PURPOSE: Our group had recently described human hand Pacinian corpuscles (PCs): the hand PCs are not simply arranged along the digital palmar nerves but often exhibited specific morphologies known uncommonly. However, there is still no or few information about human foot PCs. MATERIALS AND METHODS: We observed transverse sections of all five toes including the interdigital area obtained from 12 feet of eight fetuses at 28-33 weeks (crown-rump length 230-290mm). Serial sections were prepared for 3D reconstructions and measurement. RESULTS: Foot PCs were characterized by (1) a dense distribution in the interdigital area in contrast to a few PCs in the distal tip of the all five toes; (2) abundant dorsal PCs including those in the nail bed and: (3) a long chain of PCs in the flexor tendon sheath of all five toes. Therefore, a distal dominance was not evident in the foot in contrast to the hand and, a tendon sheath contained much greater numbers of PCs than the hand. A tree-like or bouquet-like arrangement of PCs along a short perforating artery to the palmar digital skin was seen in the foot as we had described in the hand. The tree of foot PCs was sometimes seen laying transversely along the digital skin surface, not toward the skin. CONCLUSION: It is still unknown that, in utero, how the PCs distribution became different between the hand and foot: it might be determined genetically in a region-specific manner.
PURPOSE: Our group had recently described human hand Pacinian corpuscles (PCs): the hand PCs are not simply arranged along the digital palmar nerves but often exhibited specific morphologies known uncommonly. However, there is still no or few information about human foot PCs. MATERIALS AND METHODS: We observed transverse sections of all five toes including the interdigital area obtained from 12 feet of eight fetuses at 28-33 weeks (crown-rump length 230-290mm). Serial sections were prepared for 3D reconstructions and measurement. RESULTS: Foot PCs were characterized by (1) a dense distribution in the interdigital area in contrast to a few PCs in the distal tip of the all five toes; (2) abundant dorsal PCs including those in the nail bed and: (3) a long chain of PCs in the flexor tendon sheath of all five toes. Therefore, a distal dominance was not evident in the foot in contrast to the hand and, a tendon sheath contained much greater numbers of PCs than the hand. A tree-like or bouquet-like arrangement of PCs along a short perforating artery to the palmar digital skin was seen in the foot as we had described in the hand. The tree of foot PCs was sometimes seen laying transversely along the digital skin surface, not toward the skin. CONCLUSION: It is still unknown that, in utero, how the PCs distribution became different between the hand and foot: it might be determined genetically in a region-specific manner.
Authors: Jorge Feito; Ruth Esteban; María Lourdes García-Martínez; Francisco J García-Alonso; Raquel Rodríguez-Martín; María Belén Rivas-Marcos; Juan L Cobo; Benjamín Martín-Biedma; Manuel Lahoz; José A Vega Journal: Diagnostics (Basel) Date: 2022-07-13