Literature DB >> 31563189

It's Time to Start Phenotyping Our Patients with Asthma.

Hannah Duffey1, William C Anderson2.   

Abstract

Advances in the management of pediatric asthma, including biologics, offer practitioners the ability to tailor therapies to individual patients. However, asthma treatment guidelines have not kept up with current studies. This review explores the current literature incorporating the use of phenotyping in pediatric patients with asthma to provide precision therapy. Biomarkers can be used to more accurately predict the development of asthma, identify features that may be associated with difficult-to-control or severe asthma, and forecast response to therapies. Biomarkers and other phenotypic data can also be helpful in patients with uncontrolled, severe asthma in the selection of a biologic therapy.
Copyright © 2019 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Asthma; Biologic; Biomarker; Controller; Endotype; Management; Pediatric; Phenotype

Mesh:

Substances:

Year:  2019        PMID: 31563189     DOI: 10.1016/j.iac.2019.07.009

Source DB:  PubMed          Journal:  Immunol Allergy Clin North Am        ISSN: 0889-8561            Impact factor:   3.479


  2 in total

1.  Severe asthma in children: Description of a large multidisciplinary clinical cohort.

Authors:  Maria Forero Molina; William Okoniewski; Sandeep Puranik; Shean Aujla; Juan C Celedón; Allyson Larkin; Erick Forno
Journal:  Pediatr Pulmonol       Date:  2022-03-23

Review 2.  The diagnosis of asthma. Can physiological tests of small airways function help?

Authors:  Mohammed A Almeshari; James Stockley; Elizabeth Sapey
Journal:  Chron Respir Dis       Date:  2021 Jan-Dec       Impact factor: 2.444

  2 in total

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