Literature DB >> 31559844

Effect of manual therapy in patients with hemophilia and ankle arthropathy: a randomized clinical trial.

Elena Donoso-Úbeda1, Javier Meroño-Gallut2, José Antonio López-Pina3, Rubén Cuesta-Barriuso4,5,6.   

Abstract

OBJECTIVE: The aim of this study was to evaluate the effects of a manual therapy using fascial therapy on joint bleeding, joint pain and joint function in patients with hemophilic ankle arthropathy.
SETTING: Hemophilia patient associations.
DESIGN: Randomized, controlled trial, multicenter and intention-to-treat analysis. PARTICIPANTS: A total of 65 patients with hemophilic ankle arthropathy. INTERVENTION: The experimental group (n = 33) received one fascial therapy session per week for three weeks. The control group (n = 32) received no treatment. OUTCOME MEASURE: The primary outcome was frequency of joint bleeding measured using self-reporting. Secondary outcomes were joint pain (under load-bearing and non-load-bearing conditions) measured using the visual analog scale; joint condition was measured using the Hemophilia Joint Health Score. Outcomes were measured at baseline, posttreatment and after five months of follow-up.
RESULTS: Improvements in the frequency joint bleeding at T0, T1 and T2 were significantly higher in the experimental group (T0: mean (SD) = 1.56 (1.30); T1: mean (SD) = 0.00 (0.00); T2: mean (SD) = 0.27 (0.57)) compared to the control group (T0: mean (SD) = 1.70 (1.78); T1: mean (SD) = 0.05 (0.21); T2: mean (SD) = 0.58 (0.85)). Mean improvement of joint state after the study period was 1.74 points (±1.66) for patients in the experimental group, while the control group exhibited a joint deterioration with 0.43 points (±0.85). Ankle joint pain under load-bearing and non-load-bearing conditions improved in the experimental group with -1.72 (±1.86) and -0.50 (±1.39) points, respectively.
CONCLUSION: The study showed that fascial therapy is favorable for patients with hemophilic ankle arthropathy.

Entities:  

Keywords:  Hemophilia; ankle arthropathy; fascial therapy; physical therapy; randomized clinical trial

Mesh:

Year:  2019        PMID: 31559844     DOI: 10.1177/0269215519879212

Source DB:  PubMed          Journal:  Clin Rehabil        ISSN: 0269-2155            Impact factor:   3.477


  2 in total

Review 1.  Ankle hemophilic arthropathy: literature review.

Authors:  Tommaso Greco; Chiara Polichetti; Adriano Cannella; Vincenzo La Vergata; Giulio Maccauro; Carlo Perisano
Journal:  Am J Blood Res       Date:  2021-06-15

2.  Effectiveness of rehabilitation on pain and function in people affected by hemophilia.

Authors:  Dalila Scaturro; Maria Grazia Benedetti; Giulia Lomonaco; Sofia Tomasello; Maria Grazia Giuseppina Farella; Giuseppina Passantino; Antonio Frizziero; Giulia Letizia Mauro
Journal:  Medicine (Baltimore)       Date:  2021-12-17       Impact factor: 1.817

  2 in total

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