Literature DB >> 31559242

Coexisting Optic Disc Melanocytoma and Pituitary Adenoma.

Yamini Attiku1, Pukhraj Rishi1, Shikha Bassi2.   

Abstract

AIM: To report a rare case of optic disc melanocytoma coexistent with pituitary adenoma.
METHODS: Ophthalmological examination with perimetry and magnetic resonance imaging (MRI) of the brain and orbits was done.
RESULTS: A 42-year-old woman presented with complaints of progressive diminution of vision in the right eye of 6 weeks' duration. Visual acuity in the affected right eye was 6/60 and in the left eye it was 6/6. On examination, a brown-black lesion was noted over the optic nerve head in the right eye. On perimetry, the visual field was constricted in the right eye and a superior altitudinal defect was found in the left eye. MRI of the brain and orbits revealed a pituitary adenoma with suprasellar extension. The patient underwent endoscopic transphenoidal pituitary adenoma excision with uneventful recovery. Three months following surgery, visual acuity improved to 6/6 in both eyes with partial visual field recovery and was maintained at 10 months of follow-up. There was no recurrence or metastasis.
CONCLUSION: A high degree of suspicion is required to screen for possible coexistent orbital or central nervous system pathology in cases of optic disc melanocytoma with disproportionate signs or symptoms.

Entities:  

Keywords:  Eye; Hamartoma; Optic disc melanocytoma; Pituitary adenoma; Tumor; Visual field

Year:  2019        PMID: 31559242      PMCID: PMC6751454          DOI: 10.1159/000496149

Source DB:  PubMed          Journal:  Ocul Oncol Pathol        ISSN: 2296-4657


  10 in total

1.  Central retinal artery occlusion secondary to optic disk melanocytoma.

Authors:  Pukhraj Rishi; Ramesh Venkatesh
Journal:  Retin Cases Brief Rep       Date:  2012

2.  Visual disturbance in patients with melanocytoma of the optic disk.

Authors:  T Usui; M Shirakashi; A Kurosawa; H Abe; K Iwata
Journal:  Ophthalmologica       Date:  1990       Impact factor: 3.250

3.  Pupillary and visual field evaluation in patients with melanocytoma of the optic disc.

Authors:  R H Osher; J A Shields; P R Layman
Journal:  Arch Ophthalmol       Date:  1979-06

4.  Bilateral melanocytoma of the optic nerve associated with intracranial meningioma.

Authors:  T J Walsh; S Packer
Journal:  Ann Ophthalmol       Date:  1971-08

Review 5.  Melanocytoma of the optic disk: a review.

Authors:  Jerry A Shields; Hakan Demirci; Arman Mashayekhi; Ralph C Eagle; Carol L Shields
Journal:  Surv Ophthalmol       Date:  2006 Mar-Apr       Impact factor: 6.048

6.  Melanocytoma of the left optic nerve head and right retrobulbar optic neuropathy compressed by a tuberculum sellae meningioma.

Authors:  K Shinoda; S Hayasaka; Y Nagaki; C Kadoi; M Kurimoto; E Okada
Journal:  Ophthalmologica       Date:  2000       Impact factor: 3.250

7.  Melanocytomas of the optic disk.

Authors:  Leonidas Zografos; Chantal Bornet Othenin-Girard; Laurence Desjardins; Ann Schalenbourg; Line Chamot; Sylvie Uffer
Journal:  Am J Ophthalmol       Date:  2004-12       Impact factor: 5.258

8.  Clinical and follow-up studies of melanocytomas of the optic disc.

Authors:  L Joffe; J A Shields; R H Osher; J D Gass
Journal:  Ophthalmology       Date:  1979-06       Impact factor: 12.079

9.  Melanocytoma of optic disc in 115 cases: the 2004 Samuel Johnson Memorial Lecture, part 1.

Authors:  Jerry A Shields; Hakan Demirci; Arman Mashayekhi; Carol L Shields
Journal:  Ophthalmology       Date:  2004-09       Impact factor: 12.079

10.  Melanocytoma of the optic disc.

Authors:  T W Archdale; D E Magnus
Journal:  J Am Optom Assoc       Date:  1993-02
  10 in total
  1 in total

1.  Bilateral Congenital Ptosis Associated with Optic Disc Melanocytoma.

Authors:  Abdulrahman H Badawi; Huda Al-Ghadeer
Journal:  Middle East Afr J Ophthalmol       Date:  2021-04-30
  1 in total

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