Maria Rita Lo Monaco1, Enrico Di Stasio2, Giuseppe Zuccalà3, Martina Petracca4, Danilo Genovese4, Domenico Fusco3, Maria Caterina Silveri5, Rosa Liperoti3, Diego Ricciardi6, Maria Camilla Cipriani3, Alice Laudisio7, Anna Rita Bentivoglio8. 1. Fondazione Policlinico Universitario Agostino Gemelli, IRCCS (MRLM, EDS, GZ, DF, RL, DR, MCC, ARB), Rome, Italy; Institute of Internal Medicine and Geriatrics, Università Cattolica del Sacro Cuore (MRLM, GZ, DF, RL, MCC), Rome, Italy. Electronic address: rita.lomonaco@gmail.com. 2. Fondazione Policlinico Universitario Agostino Gemelli, IRCCS (MRLM, EDS, GZ, DF, RL, DR, MCC, ARB), Rome, Italy; Istituto di Biochimica e Biochimica Clinica, Università Cattolica del Sacro Cuore (EDS), Rome, Italy. 3. Fondazione Policlinico Universitario Agostino Gemelli, IRCCS (MRLM, EDS, GZ, DF, RL, DR, MCC, ARB), Rome, Italy; Institute of Internal Medicine and Geriatrics, Università Cattolica del Sacro Cuore (MRLM, GZ, DF, RL, MCC), Rome, Italy. 4. Institute of Neurology, Università Cattolica del Sacro Cuore (MP, DG, ARB), Rome, Italy. 5. Department of Psychology, Università Cattolica del Sacro Cuore (MCS), Milan, Italy. 6. Fondazione Policlinico Universitario Agostino Gemelli, IRCCS (MRLM, EDS, GZ, DF, RL, DR, MCC, ARB), Rome, Italy. 7. Unit of Geriatrics, Department of Medicine, Campus Bio-Medico di Roma University (AL), Rome, Italy. 8. Fondazione Policlinico Universitario Agostino Gemelli, IRCCS (MRLM, EDS, GZ, DF, RL, DR, MCC, ARB), Rome, Italy; Institute of Neurology, Università Cattolica del Sacro Cuore (MP, DG, ARB), Rome, Italy.
Abstract
BACKGROUND: The clinical picture of obsessive-compulsive disorder encompasses a broad range of symptoms that are related to multiple psychological domains, including perception, cognition, emotion, and social relatedness. As obsessive-compulsive symptoms (OCS) frequently have an early onset, there are limited data about OCS in older populations (≥65 years) and, in particular, in elderly subjects with Parkinson disease (PD). OBJECTIVE: This study aimed to estimate the prevalence of OCS using a self-report measure (Obsessive-Compulsive Inventory-Revised) and to identify associated sociodemographic and clinical factors in a sample of elderly PD patients compared to a comparison group of similarly aged healthy volunteers. RESULTS: The mean age was 74 ± 6 years in the PD patients and 73 ± 7 years in the comparison group. The mean disease duration was 9.6 ± 5.8 years. Among the PD patients, 30.7% reported at least one OCS or a related disorder compared to 21.1% in the comparison group. Hoarding was significantly more common in PD patients than in the comparison group. CONCLUSIONS: Subclinical OCS were present at a high percentage in both PD patients and comparison group. The OCS phenotype in PD may present differently, as hoarding was more common in PD patients.
BACKGROUND: The clinical picture of obsessive-compulsive disorder encompasses a broad range of symptoms that are related to multiple psychological domains, including perception, cognition, emotion, and social relatedness. As obsessive-compulsive symptoms (OCS) frequently have an early onset, there are limited data about OCS in older populations (≥65 years) and, in particular, in elderly subjects with Parkinson disease (PD). OBJECTIVE: This study aimed to estimate the prevalence of OCS using a self-report measure (Obsessive-Compulsive Inventory-Revised) and to identify associated sociodemographic and clinical factors in a sample of elderly PDpatients compared to a comparison group of similarly aged healthy volunteers. RESULTS: The mean age was 74 ± 6 years in the PDpatients and 73 ± 7 years in the comparison group. The mean disease duration was 9.6 ± 5.8 years. Among the PDpatients, 30.7% reported at least one OCS or a related disorder compared to 21.1% in the comparison group. Hoarding was significantly more common in PDpatients than in the comparison group. CONCLUSIONS: Subclinical OCS were present at a high percentage in both PDpatients and comparison group. The OCS phenotype in PD may present differently, as hoarding was more common in PDpatients.
Authors: Delfina Janiri; Martina Petracca; Lorenzo Moccia; Luca Tricoli; Carla Piano; Francesco Bove; Isabella Imbimbo; Alessio Simonetti; Marco Di Nicola; Gabriele Sani; Paolo Calabresi; Anna Rita Bentivoglio Journal: Front Psychiatry Date: 2020-11-27 Impact factor: 4.157