[The efficacy of a maintenance dose of 100 mg doxycycline (Vibramycin) daily in bacterial infections of chronic bronchitis (author's transl)].

The efficacy and tolerance of a daily maintenance dose of 100 mg doxycycline (Vibramycin) was investigated in ambulant patients with chronic obstructive pulmonary disease (COPD) and bacterial infection by an open study with clinical, bacteriological and cytological control. The dosage was well tolerated and effective in the elimination of H. influenzae and pneumococci. A higher maintenance dose seems not to be necessary for this type of infections.