Esther Yuet Ying Lau1, Kristy Nga Ting Lau2, Christian S Chan3, Chia-Huei Tseng4, Yeuk Ching Lam5, Desiree Man-Sik Tse5, Wing Yee Cheng5, Ka-Fai Chung6, Yun Kwok Wing7. 1. Department of Psychology, The Education University of Hong Kong, 10 Lo Ping Road, Tai Po, New Territories, Hong Kong; Centre for Psychosocial Health, The Education University of Hong Kong, Hong Kong; Department of Psychiatry, Queen Mary Hospital, The University of Hong Kong, Hong Kong. Electronic address: laueyy@eduhk.hk. 2. Clinical Psychological Services, Hong Kong Children & Youth Services, Hong Kong. 3. Department of Psychology, The University of Hong Kong, Hong Kong. 4. Research Institute of Electrical Communication, Tohoku University, Sendai, Japan. 5. Department of Psychology, The Education University of Hong Kong, 10 Lo Ping Road, Tai Po, New Territories, Hong Kong; Centre for Psychosocial Health, The Education University of Hong Kong, Hong Kong. 6. Department of Psychiatry, Queen Mary Hospital, The University of Hong Kong, Hong Kong. 7. Sleep Assessment Unit, Department of Psychiatry, The Chinese University of Hong Kong, Hong Kong.
Abstract
BACKGROUND: It has been theoretically proposed that alteration in sleep physiology may contribute to the development of biased emotional processing featured in depression. The current study investigated the role of sleep and especially REM in modulating perception of emotional faces in depressed versus non-depressed individuals using a napping paradigm. METHODS: Forty-six individuals with major depressive disorder and 66 age- and education-matched healthy controls completed an emotional face perception task before and after random assignment to one of the three intention-to-treat (ITT) conditions, namely 30-min-nap, 90-min-nap and wake. To delineate the effects of REM, as-treated (30-min-nap, 90-min-REM-nap, 90-min-noREM-nap and wake) analyses were also conducted. RESULTS: Repeated measures multivariate analysis of covariance (MANCOVA) showed a significant Time *Group *Condition interaction on angry faces for both analyses of ITT (p = .017) and AT (p = .027). Pairwise comparison with Bonferroni corrections revealed a significant increase in the intensity rating of angry faces only after 90-min-REM-nap in the depressed group. Correlational analyses convergingly showed that the increase of intensity rating of angry faces was associated with the proportion of REM sleep in the depressed group, p = .035. LIMITATIONS: The observed effect of REM sleep during daytime napping may not represent the effect of nighttime REM sleep in depression. CONCLUSIONS: We provide the first evidence of the association of daytime sleep, particularly REM sleep, with a more negative perception of angry faces exclusively in individuals with depression. The differentiated impact of sleep observed may contribute to the development of altered emotional processing in depression.
BACKGROUND: It has been theoretically proposed that alteration in sleep physiology may contribute to the development of biased emotional processing featured in depression. The current study investigated the role of sleep and especially REM in modulating perception of emotional faces in depressed versus non-depressed individuals using a napping paradigm. METHODS: Forty-six individuals with major depressive disorder and 66 age- and education-matched healthy controls completed an emotional face perception task before and after random assignment to one of the three intention-to-treat (ITT) conditions, namely 30-min-nap, 90-min-nap and wake. To delineate the effects of REM, as-treated (30-min-nap, 90-min-REM-nap, 90-min-noREM-nap and wake) analyses were also conducted. RESULTS: Repeated measures multivariate analysis of covariance (MANCOVA) showed a significant Time *Group *Condition interaction on angry faces for both analyses of ITT (p = .017) and AT (p = .027). Pairwise comparison with Bonferroni corrections revealed a significant increase in the intensity rating of angry faces only after 90-min-REM-nap in the depressed group. Correlational analyses convergingly showed that the increase of intensity rating of angry faces was associated with the proportion of REM sleep in the depressed group, p = .035. LIMITATIONS: The observed effect of REM sleep during daytime napping may not represent the effect of nighttime REM sleep in depression. CONCLUSIONS: We provide the first evidence of the association of daytime sleep, particularly REM sleep, with a more negative perception of angry faces exclusively in individuals with depression. The differentiated impact of sleep observed may contribute to the development of altered emotional processing in depression.
Authors: Mitha Al Balushi; Sara Al Balushi; Syed Javaid; Andrea Leinberger-Jabari; Fatma Al-Maskari; Mohammed Al-Houqani; Ayesha Al Dhaheri; Abdullah Al Nuaimi; Abdullah Al Junaibi; Naima Oumeziane; Marina Kazim; Aisha Al Hamiz; Muna Haji; Ayesha Al Hosani; Leila Abdel Wareth; Wael AlMahmeed; Habiba Alsafar; Fatme AlAnouti; Eiman Al Zaabi; Claire K Inman; Omar El Shahawy; Michael Weitzman; Ann Marie Schmidt; Scott Sherman; Abdishakur Abdulle; Amar Ahmad; Raghib Ali Journal: BMC Psychol Date: 2022-10-21
Authors: Gosia Lipinska; Holly Austin; Jasmin R Moonsamy; Michelle Henry; Raphaella Lewis; David S Baldwin; Kevin G F Thomas; Beth Stuart Journal: Front Behav Neurosci Date: 2022-10-04 Impact factor: 3.617