Literature DB >> 31543931

A Coding Scheme for Nucleic Acid Memory (NAM).

Kelsey Suyehira1, Simon Llewellyn2, Reza M Zadegan3, William L Hughes4, Tim Andersen5.   

Abstract

The global demand for digital data is projected to be greater than the supply of semiconductor grade silicon in 2040 [1]. When combined with the need to archive information [2], nucleic acids are being explored as an alternative memory material [1-7]. According to a recent study, the information density of nucleic acid memory (NAM) is 1000 times greater than flash memory and has the ability to last for hundreds of years [1]. Presented here is an algorithm for converting digital data into unique DNA sequences for glacial storage. Biologically inspired, our coding scheme maps hexadecimal characters to sequences of three DNA nucleotides. This mapping avoids repeating sequences and start codons, which could have adverse effects. We were able to encode and decode various file types without error.

Entities:  

Keywords:  Coding; DNA; Data storage; NAM; Nucleic Acid Memory

Year:  2017        PMID: 31543931      PMCID: PMC6754107          DOI: 10.1109/WMED.2017.7916922

Source DB:  PubMed          Journal:  IEEE Workshop Microelectron Electron Devices        ISSN: 1947-3842


  6 in total

1.  Hiding messages in DNA microdots.

Authors:  C T Clelland; V Risca; C Bancroft
Journal:  Nature       Date:  1999-06-10       Impact factor: 49.962

2.  Robust chemical preservation of digital information on DNA in silica with error-correcting codes.

Authors:  Robert N Grass; Reinhard Heckel; Michela Puddu; Daniela Paunescu; Wendelin J Stark
Journal:  Angew Chem Int Ed Engl       Date:  2015-02-04       Impact factor: 15.336

3.  Next-generation digital information storage in DNA.

Authors:  George M Church; Yuan Gao; Sriram Kosuri
Journal:  Science       Date:  2012-08-16       Impact factor: 47.728

4.  Towards practical, high-capacity, low-maintenance information storage in synthesized DNA.

Authors:  Nick Goldman; Paul Bertone; Siyuan Chen; Christophe Dessimoz; Emily M LeProust; Botond Sipos; Ewan Birney
Journal:  Nature       Date:  2013-01-23       Impact factor: 49.962

5.  Nucleic acid memory.

Authors:  Victor Zhirnov; Reza M Zadegan; Gurtej S Sandhu; George M Church; William L Hughes
Journal:  Nat Mater       Date:  2016-04       Impact factor: 43.841

6.  A Rewritable, Random-Access DNA-Based Storage System.

Authors:  S M Hossein Tabatabaei Yazdi; Yongbo Yuan; Jian Ma; Huimin Zhao; Olgica Milenkovic
Journal:  Sci Rep       Date:  2015-09-18       Impact factor: 4.379

  6 in total

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