| Literature DB >> 31543210 |
Yutaka Shimomura1, Ryan O'Shaughnessy2, Neil Rajan3.
Abstract
Trichilemmal or "pilar" cysts are commonly found on the scalp and are derived from the outer root sheath of the hair follicle. Multiple trichilemmal cysts present in an autosomal dominant pattern of inheritance, yet the genetic mechanism has remained elusive. In this issue, Hörer et al. (2019) highlight predisposing variants in PLCD1 in such families and propose a monoallelic mutational mechanism that drives cyst formation.Entities:
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Year: 2019 PMID： 31543210 DOI： 10.1016/j.jid.2019.05.027
Source DB: PubMed Journal: J Invest Dermatol ISSN： 0022-202X Impact factor: 8.551