Literature DB >> 31541865

Peptide nucleic acid (PNA) and its applications in chemical biology, diagnostics, and therapeutics.

Jacques Saarbach1, Pramod M Sabale1, Nicolas Winssinger2.   

Abstract

Peptide nucleic acid (PNA) stands as one of the most successful artificial oligonucleotide mimetics. Salient features include the stability of hybridization complexes (either as duplexes or triplexes), metabolic stability, and ease of chemical modifications. These features have enabled important applications such as antisense agents, gene editing, nucleic acid sensing and as a platform to program the assembly of PNA-tagged molecules. Here, we review recent advances in these areas.
Copyright © 2019 Elsevier Ltd. All rights reserved.

Entities:  

Year:  2019        PMID： 31541865     DOI： 10.1016/j.cbpa.2019.06.006

Source DB:  PubMed          Journal:  Curr Opin Chem Biol        ISSN： 1367-5931            Impact factor:   8.822


  20 in total

Review 1.  Perspectives on conformationally constrained peptide nucleic acid (PNA): insights into the structural design, properties and applications.

Authors:  Chaturong Suparpprom; Tirayut Vilaivan
Journal:  RSC Chem Biol       Date:  2022-03-18

2.  Simultaneous Targeting of Multiple oncomiRs with Phosphorothioate or PNA-Based Anti-miRs in Lymphoma Cell Lines.

Authors:  Karishma Dhuri; Sai Pallavi Pradeep; Jason Shi; Eleni Anastasiadou; Frank J Slack; Anisha Gupta; Xiao-Bo Zhong; Raman Bahal
Journal:  Pharm Res       Date:  2022-09-07       Impact factor: 4.580

3.  Cellular uptake of 2-aminopyridine-modified peptide nucleic acids conjugated with cell-penetrating peptides.

Authors:  Nikita Brodyagin; Yuka Kataoka; Ilze Kumpina; Dennis W McGee; Eriks Rozners
Journal:  Biopolymers       Date:  2021-12-16       Impact factor: 2.240

4.  Next generation miRNA inhibition using short anti-seed PNAs encapsulated in PLGA nanoparticles.

Authors:  Shipra Malik; Jihoon Lim; Frank J Slack; Demetrios T Braddock; Raman Bahal
Journal:  J Control Release       Date:  2020-08-21       Impact factor: 9.776

5.  PNA-Assisted DNAzymes to Cleave Double-Stranded DNA for Genetic Engineering with High Sequence Fidelity.

Authors:  Mingkuan Lyu; Linggen Kong; Zhenglin Yang; Yuting Wu; Claire E McGhee; Yi Lu
Journal:  J Am Chem Soc       Date:  2021-06-22       Impact factor: 16.383

6.  The 2-Aminopyridine Nucleobase Improves Triple-Helical Recognition of RNA and DNA When Used Instead of Pseudoisocytosine in Peptide Nucleic Acids.

Authors:  Christopher A Ryan; Nikita Brodyagin; Justin Lok; Eriks Rozners
Journal:  Biochemistry       Date:  2021-06-07       Impact factor: 3.321

7.  Cell-Penetrating Streptavidin: A General Tool for Bifunctional Delivery with Spatiotemporal Control, Mediated by Transport Systems Such as Adaptive Benzopolysulfane Networks.

Authors:  Javier López-Andarias; Jacques Saarbach; Dimitri Moreau; Yangyang Cheng; Emmanuel Derivery; Quentin Laurent; Marcos González-Gaitán; Nicolas Winssinger; Naomi Sakai; Stefan Matile
Journal:  J Am Chem Soc       Date:  2020-02-28       Impact factor: 15.419

Review 8.  Antibacterial Peptide Nucleic Acids-Facts and Perspectives.

Authors:  Monika Wojciechowska; Marcin Równicki; Adam Mieczkowski; Joanna Miszkiewicz; Joanna Trylska
Journal:  Molecules       Date:  2020-01-28       Impact factor: 4.411

Review 9.  Theranostic Pretargeting Drug Delivery and Imaging Platforms in Cancer Precision Medicine.

Authors:  Sudath Hapuarachchige; Dmitri Artemov
Journal:  Front Oncol       Date:  2020-07-22       Impact factor: 6.244

10.  Exploring miR-9 Involvement in Ciona intestinalis Neural Development Using Peptide Nucleic Acids.

Authors:  Silvia Mercurio; Silvia Cauteruccio; Raoul Manenti; Simona Candiani; Giorgio Scarì; Emanuela Licandro; Roberta Pennati
Journal:  Int J Mol Sci       Date:  2020-03-15       Impact factor: 5.923
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