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Literature DB >> 31539497

SnapShot: The RNA Exosome.

M Rhyan Puno¹, Eva-Maria Weick¹, Mom Das¹, Christopher D Lima².

Abstract

The RNA exosome is a 3' to 5' ribonuclease that plays a fundamental role in maturation, quality control, and turnover of nearly all types of RNA produced in eukaryotic cells. Here, we present an overview of the structure, composition, and functions of the RNA exosome, including various cytoplasmic and nuclear exosome co-factors and associated protein complexes. To view this SnapShot, open or download the PDF.

Entities: Gene

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Year: 2019 PMID： 31539497 DOI： 10.1016/j.cell.2019.09.005

Source DB: PubMed Journal: Cell ISSN： 0092-8674 Impact factor: 41.582

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Cited

10 in total

Review 1. The Integrator Complex in Transcription and Development.

Authors: María Saraí Mendoza-Figueroa; Deirdre C Tatomer; Jeremy E Wilusz
Journal: Trends Biochem Sci Date: 2020-08-13 Impact factor: 13.807

2. Structural basis for RNA surveillance by the human nuclear exosome targeting (NEXT) complex.

Authors: M Rhyan Puno; Christopher D Lima
Journal: Cell Date: 2022-06-09 Impact factor: 66.850

Review 3. Molecular characteristics and functional differences of anti-PM/Scl autoantibodies and two other distinct and unique supramolecular structures known as "EXOSOMES".

Authors: Peter J Wermuth; Sergio A Jimenez
Journal: Autoimmun Rev Date: 2020-08-12 Impact factor: 9.754

Review 4. RNA helicases are hubs that orchestrate exosome-dependent 3'-5' decay.

Authors: Eva-Maria Weick; Christopher D Lima
Journal: Curr Opin Struct Biol Date: 2020-11-02 Impact factor: 6.809

5. Substrate discrimination and quality control require each catalytic activity of TRAMP and the nuclear RNA exosome.

Authors: Mom Das; Dimitrios Zattas; John C Zinder; Elizabeth V Wasmuth; Julien Henri; Christopher D Lima
Journal: Proc Natl Acad Sci U S A Date: 2021-04-06 Impact factor: 12.779

6. Extracellular vesicles derived from neural EGFL-Like 1-modified mesenchymal stem cells improve acellular bone regeneration via the miR-25-5p-SMAD2 signaling axis.

Authors: Yanhua Lan; Huizhi Xie; Qianrui Jin; Xiaomin Zhao; Yang Shi; Yanyan Zhou; Zihe Hu; Yi Ye; Xiaoyuan Huang; Yingjia Sun; Zhuo Chen; Zhijian Xie
Journal: Bioact Mater Date: 2022-01-19

SnapShot: The RNA Exosome.

Review 1. The Integrator Complex in Transcription and Development.

2. Structural basis for RNA surveillance by the human nuclear exosome targeting (NEXT) complex.

Review 3. Molecular characteristics and functional differences of anti-PM/Scl autoantibodies and two other distinct and unique supramolecular structures known as "EXOSOMES".

Review 4. RNA helicases are hubs that orchestrate exosome-dependent 3'-5' decay.

5. Substrate discrimination and quality control require each catalytic activity of TRAMP and the nuclear RNA exosome.

6. Extracellular vesicles derived from neural EGFL-Like 1-modified mesenchymal stem cells improve acellular bone regeneration via the miR-25-5p-SMAD2 signaling axis.

7. Atypical hemolytic uremic syndrome induced by SARS-CoV2 infection in infants with EXOSC3 mutation.

8. Methods to assess helicase and translocation activities of human nuclear RNA exosome and RNA adaptor complexes.

Review 9. Immune status for monitoring and treatment of bladder cancer.

Review 10. Catalytic activities, molecular connections, and biological functions of plant RNA exosome complexes.