Literature DB >> 31539318

Primary leiomyosarcoma of cervical spine invading the vertebra without obvious osteoclasia: Case report and literature review.

Han Sun1, Min Zhuang1, Dong Cheng1, Chenlei Zhu1, Zhiwei Liu1, Xubin Qiu1.   

Abstract

Context: Primary leiomyosarcomas are malignant tumors of smooth muscles, with few reported cases occurring in the cervical spine. The authors report a case involving a 29-year-old man with primary leiomyosarcoma in the spinal canal posterior to the C3-C5 vertebrae.Findings: No obvious osteolytic lesions could be found in neither X-ray nor computed tomography scan. Because of the confusion of nontypical imaging findings, a decompressive surgery of anterior cervical corpectomy of C4 and reconstruction with a mesh cage filled with allogenic bone grafts were performed. The patient refused a second operation and then was advised to receive the radiotherapy. No recurrence of the symptoms was evident 6 months after surgery.
Conclusion: When a patient suffers from upper cervical tumor, the leiomyosarcoma should be kept in mind as possible diagnoses despite its low occurring ratio. Early detection, early diagnosis, and early treatment must be the goal of the strategy.

Entities:  

Keywords:  Cervical spine; Corpectomy; Leiomyosarcoma; Osteoclasia; Smooth muscle

Mesh:

Year:  2019        PMID: 31539318      PMCID: PMC9246264          DOI: 10.1080/10790268.2019.1656848

Source DB:  PubMed          Journal:  J Spinal Cord Med        ISSN: 1079-0268            Impact factor:   2.040


  5 in total

1.  Primary leiomyosarcoma of the cervical spine causing spontaneous compression fracture: report of an autopsy case.

Authors:  H Ochiai; Y Yamakawa; T Fukushima; H Yamada; T Hayashi
Journal:  Neuropathology       Date:  2000-03       Impact factor: 1.906

Review 2.  Primary extradural epithelioid leiomyosarcoma of the cervical spine: case report and literature review.

Authors:  Laurence A G Marshman; Jonathan R Pollock; Andrew King; Sanjiv J Chawda
Journal:  Neurosurgery       Date:  2005-08       Impact factor: 4.654

3.  Case Report: A Low-grade Uterine Leiomyosarcoma Showing Multiple Genetic Aberrations Including a Bi-allelic Loss of the Retinoblastoma Gene Locus, as well as Germ-line Uniparental Disomy for Part of the Long Arm of Chromosome 22.

Authors:  Carsten Holzmann; Dirk Koczan; Thomas Loening; Birgit Rommel; Joern Bullerdiek
Journal:  Anticancer Res       Date:  2017-05       Impact factor: 2.480

4.  Partial spondylectomy for primary leiomyosarcoma of C2 vertebra.

Authors:  Hasan Kamil Sucu; Hamdi Bezircioğlu; Türkan Rezanko
Journal:  Spine (Phila Pa 1976)       Date:  2011-10-01       Impact factor: 3.468

5.  Leiomyosarcoma of the hypopharynx: a case report.

Authors:  Toshitaka Takahashi; Ryuzaburo Higo; Hiroto Nakata; Masashi Sugasawa
Journal:  Auris Nasus Larynx       Date:  2008-02-06       Impact factor: 1.863

  5 in total

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