| Literature DB >> 31538260 |
Sepideh Saroukhani1,2, Maureen Samms-Vaughan3, MinJae Lee2,4, MacKinsey A Bach1,2, Jan Bressler1,5, Manouchehr Hessabi2, Megan L Grove1,5, Sydonnie Shakespeare-Pellington3, Katherine A Loveland6, Mohammad H Rahbar7,8,9.
Abstract
Mode of delivery, preterm birth, and low birth weight (LBW) are hypothesized to be associated with autism spectrum disorder (ASD) in the offspring. Using data from 343 ASD cases (2-8 years) and their age- and sex-matched typically developing controls in Jamaica we investigated these hypotheses. Our statistical analyses revealed that the parish of residence could modify the association between cesarean delivery and ASD, with a difference found in this relationship in Kingston parish [matched odds ratio (MOR) (95% confidence interval (CI)) 2.30 (1.17-4.53)] and other parishes [MOR (95% CI) 0.87 (0.48-1.59)]. Although the associations of LBW and preterm birth with ASD were not significant, we observed a significant interaction between LBW and the household socioeconomic status. These findings require replication.Entities:
Keywords: Autism spectrum disorder; Cesarean delivery; Jamaica; Low birth weight; Preterm birth
Mesh：
Year: 2020 PMID： 31538260 PMCID： PMC7080579 DOI： 10.1007/s10803-019-04229-0
Source DB: PubMed Journal: J Autism Dev Disord ISSN： 0162-3257