Literature DB >> 31537237

[Experience of continuous fluid therapy in successfully rescuing a patient with acute severe paraquat poisoning].

Enmin Feng1, Youlin Cheng, Zhihua Tan, Hailing Wang.   

Abstract

OBJECTIVE: Paraquat (PQ) poisoning has become one of the common pesticide poisoning in China. PQ is extremely toxic to human beings. The fatality rate of oral PQ poisoning is more than 90%. So far, there is no specific antidote. Seek effective treatment measures for PQ poisoning has become the focus of clinical medical research. In November 2017, a patient with acute severe PQ poisoning was treated in the intensive care unit (ICU) of Shouguang People's Hospital Affiliated to Weifang Medical College. The patient refused blood purification therapy and was rescued successfully only by continuous fluid therapy, diuresis, catharsis and routine treatment. By reviewing the treatment process of this case, new treatment ideas for the clinical treatment of PQ poisoning in primary hospitals were provided. Patients with acute PQ poisoning should be rescued by immediate administration of emetic, gastric lavage, catharsis and oral montmorillonite powder. For those without dysfunction of heart, lung and and kidney, a large amount of fluid treatment and diuresis should be given immediately to promote the excretion of poison. The key to improve the success rate of rescue of acute PQ poisoning is to eliminate PQ from the body as soon as possible.

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Year:  2019        PMID: 31537237     DOI: 10.3760/cma.j.issn.2095-4352.2019.08.027

Source DB:  PubMed          Journal:  Zhonghua Wei Zhong Bing Ji Jiu Yi Xue


  2 in total

1.  Clinical significance of serum levels of microRNA-27a and its correlation with interleukin-10 in patients with multiple organ dysfunction syndrome caused by acute paraquat poisoning.

Authors:  Huizhen Dai; Huan Zhang; Xinxia Zu; Hongyan Wang; Lili Wang
Journal:  Exp Ther Med       Date:  2020-01-02       Impact factor: 2.447

2.  Anthrahydroquinone-2-6-disulfonate is a novel, powerful antidote for paraquat poisoning.

Authors:  Jin Qian; Chun-Yuan Wu; Dong-Ming Wu; Li-Hua Li; Qi Li; Tang Deng; Qi-Feng Huang; Shuang-Qin Xu; Hang-Fei Wang; Xin-Xin Wu; Zi-Yi Cheng; Chuan-Zhu Lv; Xiao-Ran Liu
Journal:  Sci Rep       Date:  2021-10-11       Impact factor: 4.379

  2 in total

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