BACKGROUND: Infection is a serious surgical complication that significantly increases morbidity and mortality rates as well as health care expenses. Increased bacterial resistance to antibiotics makes the treatment of such events even more troublesome. OBJECTIVE: To report on a surgical infection case treated with ozone as a complementary therapy. METHODS AND MATERIALS: A female, 65 years old, submitted to a complex surgical procedure for adult kyphotic deformity correction that presented with early postsurgical infection. The patient was treated with revision surgery and antibiotics that improved the condition but were unable to delete the infection. Ozone, in its gaseous form, was injected subcutaneously and paravertebrally twice weekly for 3 weeks. RESULTS: After 3 weeks of treatment, the wound healed completely. Follow-up visits and laboratory exams for up to 1 year after surgery showed no recurrence of infection. CONCLUSIONS: Although just a single case, topical ozone therapy for surgical infections showed promising potential in this specific case.
BACKGROUND: Infection is a serious surgical complication that significantly increases morbidity and mortality rates as well as health care expenses. Increased bacterial resistance to antibiotics makes the treatment of such events even more troublesome. OBJECTIVE: To report on a surgical infection case treated with ozone as a complementary therapy. METHODS AND MATERIALS: A female, 65 years old, submitted to a complex surgical procedure for adult kyphotic deformity correction that presented with early postsurgical infection. The patient was treated with revision surgery and antibiotics that improved the condition but were unable to delete the infection. Ozone, in its gaseous form, was injected subcutaneously and paravertebrally twice weekly for 3 weeks. RESULTS: After 3 weeks of treatment, the wound healed completely. Follow-up visits and laboratory exams for up to 1 year after surgery showed no recurrence of infection. CONCLUSIONS: Although just a single case, topical ozone therapy for surgical infections showed promising potential in this specific case.
Authors: Bernard M Babior; Cindy Takeuchi; Julie Ruedi; Abel Gutierrez; Paul Wentworth Journal: Proc Natl Acad Sci U S A Date: 2003-02-24 Impact factor: 11.205
Authors: Margaret A Olsen; Jennie Mayfield; Carl Lauryssen; Louis B Polish; Marilyn Jones; Joshua Vest; Victoria J Fraser Journal: J Neurosurg Date: 2003-03 Impact factor: 5.115