Literature DB >> 31532213

Investigating Triorthogonal Chemoselectivity. Effect of Azide Substitution on the Triazine Core.

Anamika Sharma1,2, Rotimi Sheyi1, Ashish Kumar1, Ayman El-Faham3,4, Beatriz G de la Torre2, Fernando Albericio1,3,5.   

Abstract

An example of triorthogonal chemoselectivity is reported here for the first time. In this regard, a series of 43 reactions were performed using tridentate s-triazine as a model. In all of the possible cases, the three substitutions were carried out using different nucleophiles at a temperature compatible with biological systems.

Entities:  

Year:  2019        PMID: 31532213     DOI: 10.1021/acs.orglett.9b02878

Source DB:  PubMed          Journal:  Org Lett        ISSN: 1523-7052            Impact factor:   6.005


  3 in total

Review 1.  s-Triazine: A Privileged Structure for Drug Discovery and Bioconjugation.

Authors:  Anamika Sharma; Rotimi Sheyi; Beatriz G de la Torre; Ayman El-Faham; Fernando Albericio
Journal:  Molecules       Date:  2021-02-06       Impact factor: 4.411

2.  The Antiproliferative and Apoptotic Effect of a Novel Synthesized S-Triazine Dipeptide Series, and Toxicity Screening in Zebrafish Embryos.

Authors:  Azizah M Malebari; Rakia Abd Alhameed; Zainab Almarhoon; Muhammad Farooq; Mohammad A M Wadaan; Anamika Sharma; Beatriz G de la Torre; Fernando Albericio; Ayman El-Faham
Journal:  Molecules       Date:  2021-02-22       Impact factor: 4.411

3.  Synthesis of New S-Triazine Bishydrazino and Bishydrazido-Based Polymers and Their Application in Flame-Retardant Polypropylene Composites.

Authors:  Ali Aldalbahi; Bander S AlOtaibi; Badr M Thamer; Ayman El-Faham
Journal:  Polymers (Basel)       Date:  2022-02-17       Impact factor: 4.329

  3 in total

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