BACKGROUND: Research identifies highly variable prevalence estimates for autism spectrum disorder (ASD) in children and adolescents with attention deficit hyperactivity disorder (ADHD), particularly between community and clinical samples, warranting quantitative meta-analyses to investigate the true prevalence of ASD in children and adolescents with ADHD. METHODS: Studies were identified through a systematic literature search of PsycINFO, MEDLINE and Web of Science through January 2018. Twenty-two publications met inclusion criteria (total N = 61 985). Two random effects meta-analyses were conducted: (1) to identify the proportion of children and adolescents with ADHD that met criteria for ASD; and (2) to compare the severity of dimensionally-measured ASD symptomology in children and adolescents with and without ADHD. RESULTS: The overall pooled effect for children and adolescents with ADHD who met threshold for ASD was 21%. There was no significant difference between community samples (19%) and clinical samples (24%) or between US studies v. those from other countries. Children and adolescents with ADHD had substantially more dimensionally-measured ASD traits compared with those who did not have ADHD (d = 1.23). CONCLUSION: The findings provide further evidence that ADHD and ASD are associated in nature. Clinical and research implications are discussed.
BACKGROUND: Research identifies highly variable prevalence estimates for autism spectrum disorder (ASD) in children and adolescents with attention deficit hyperactivity disorder (ADHD), particularly between community and clinical samples, warranting quantitative meta-analyses to investigate the true prevalence of ASD in children and adolescents with ADHD. METHODS: Studies were identified through a systematic literature search of PsycINFO, MEDLINE and Web of Science through January 2018. Twenty-two publications met inclusion criteria (total N = 61 985). Two random effects meta-analyses were conducted: (1) to identify the proportion of children and adolescents with ADHD that met criteria for ASD; and (2) to compare the severity of dimensionally-measured ASD symptomology in children and adolescents with and without ADHD. RESULTS: The overall pooled effect for children and adolescents with ADHD who met threshold for ASD was 21%. There was no significant difference between community samples (19%) and clinical samples (24%) or between US studies v. those from other countries. Children and adolescents with ADHD had substantially more dimensionally-measured ASD traits compared with those who did not have ADHD (d = 1.23). CONCLUSION: The findings provide further evidence that ADHD and ASD are associated in nature. Clinical and research implications are discussed.
Authors: Susan Young; Philip Asherson; Tony Lloyd; Michael Absoud; Muhammad Arif; William Andrew Colley; Samuele Cortese; Sally Cubbin; Nancy Doyle; Susan Dunn Morua; Philip Ferreira-Lay; Gisli Gudjonsson; Valerie Ivens; Christine Jarvis; Alexandra Lewis; Peter Mason; Tamsin Newlove-Delgado; Mark Pitts; Helen Read; Kobus van Rensburg; Bozhena Zoritch; Caroline Skirrow Journal: Front Psychiatry Date: 2021-03-19 Impact factor: 4.157
Authors: Maria M Lilja; Emil Sandblom; Paul Lichtenstein; Eva Serlachius; Clara Hellner; Jyoti Bhagia; Linda Halldner Journal: J Neurodev Disord Date: 2022-03-06 Impact factor: 4.025
Authors: Eun Jung Choi; Marlee M Vandewouw; Margot J Taylor; Paul D Arnold; Jessica Brian; Jennifer Crosbie; Elizabeth Kelley; Meng-Chuan Lai; Xudong Liu; Russell J Schachar; Jason P Lerch; Evdokia Anagnostou Journal: Neuroimage Clin Date: 2020-10-27 Impact factor: 4.881
Authors: Susan Young; Nicoletta Adamo; Bryndís Björk Ásgeirsdóttir; Polly Branney; Michelle Beckett; William Colley; Sally Cubbin; Quinton Deeley; Emad Farrag; Gisli Gudjonsson; Peter Hill; Jack Hollingdale; Ozge Kilic; Tony Lloyd; Peter Mason; Eleni Paliokosta; Sri Perecherla; Jane Sedgwick; Caroline Skirrow; Kevin Tierney; Kobus van Rensburg; Emma Woodhouse Journal: BMC Psychiatry Date: 2020-08-12 Impact factor: 3.630