Linglan Pan1, Zhen Fu2, Ping Yin2, Dunjin Chen1. 1. Department of Obstetrics and Gynecology, The Third Affiliated Hospital of Guangzhou Medical University , Guangzhou , China. 2. Department of Epidemiology and Biostatistics and State Key Laboratory of Environment Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology , Wuhan， , China.
Abstract
Objective: We sought to explore pre-existing medical disorders as risk factors for preeclampsia as thoroughly as possible. Methods: A case-control design. A group of 1,652 patients were identified as the preeclampsia group, and another randomly selected 4,500 patients were identified as the non-preeclampsia group. Results: Mature ovarian teratoma (adjusted odds ratio [OR] 7.69, 95% CI 1.58-37.53), uterine fibroids (adjusted OR 2.24, 95% CI 1.28-3.92) and pregestational hypothyroidism (adjusted OR 5.17, 95% CI 2.43-11.00), were significantly correlated with preeclampsia. Conclusions: Mature ovarian teratoma, uterine fibroids and pregestational hypothyroidism may also contribute to the incidence of preeclampsia.
Objective: We sought to explore pre-existing medical disorders as risk factors for preeclampsia as thoroughly as possible. Methods: A case-control design. A group of 1,652 patients were identified as the preeclampsia group, and another randomly selected 4,500 patients were identified as the non-preeclampsia group. Results:Mature ovarian teratoma (adjusted odds ratio [OR] 7.69, 95% CI 1.58-37.53), uterine fibroids (adjusted OR 2.24, 95% CI 1.28-3.92) and pregestational hypothyroidism (adjusted OR 5.17, 95% CI 2.43-11.00), were significantly correlated with preeclampsia. Conclusions: Mature ovarian teratoma, uterine fibroids and pregestational hypothyroidism may also contribute to the incidence of preeclampsia.
Entities:
Keywords:
Preeclampsia; case-control study; pre-existing medical disorder; risk factors
Authors: Anadeijda J E M C Landman; Emma E Don; Guus Vissers; Hans C J Ket; Martijn A Oudijk; Christianne J M de Groot; Judith A F Huirne; Marjon A de Boer Journal: PLoS One Date: 2022-06-02 Impact factor: 3.752
Authors: Víctor Borda; Isabela Alvim; Marla Mendes; Carolina Silva-Carvalho; Giordano B Soares-Souza; Thiago P Leal; Vinicius Furlan; Marilia O Scliar; Roxana Zamudio; Camila Zolini; Gilderlanio S Araújo; Marcelo R Luizon; Carlos Padilla; Omar Cáceres; Kelly Levano; César Sánchez; Omar Trujillo; Pedro O Flores-Villanueva; Michael Dean; Silvia Fuselli; Moara Machado; Pedro E Romero; Francesca Tassi; Meredith Yeager; Timothy D O'Connor; Robert H Gilman; Eduardo Tarazona-Santos; Heinner Guio Journal: Proc Natl Acad Sci U S A Date: 2020-12-04 Impact factor: 12.779