Literature DB >> 31529671

Harnessing Evolution to Make Medicines (Nobel Lecture).

Gregory Winter1.   

Abstract

Antibody libraries and phage display have provided the key elements for the creation of a fast evolutionary system for the generation of fully human antibody medicines. Important steps leading to this development are outlined by G. Winter in his Nobel lecture.
© 2019 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

Entities:  

Keywords:  antibodies; drug development; immune system; phage display

Year:  2019        PMID： 31529671     DOI： 10.1002/anie.201909343

Source DB:  PubMed          Journal:  Angew Chem Int Ed Engl        ISSN： 1433-7851            Impact factor:   15.336


  7 in total

1.  Conformationally engineering flexible peptides on silver nanoparticles.

Authors:  Jia Xu; Tiange Gao; Lingjie Sheng; Yan Wang; Chenxi Lou; Haifang Wang; Yuanfang Liu; Aoneng Cao
Journal:  iScience       Date:  2022-05-04

Review 2.  Practically useful protein-design methods combining phylogenetic and atomistic calculations.

Authors:  Jonathan Weinstein; Olga Khersonsky; Sarel J Fleishman
Journal:  Curr Opin Struct Biol       Date:  2020-06-05       Impact factor: 6.809

Review 3. 

Authors:  Thomas Güttler; Matthias Dobbelstein; Dirk Görlich
Journal:  Biospektrum (Heidelb)       Date:  2022-02-13

4.  Acetylation-Specific Interference by Anti-Histone H3K9ac Intrabody Results in Precise Modulation of Gene Expression.

Authors:  Simonetta Lisi; Matteo Trovato; Ottavia Vitaloni; Marco Fantini; Michele Chirichella; Paola Tognini; Sara Cornuti; Mario Costa; Marco Groth; Antonino Cattaneo
Journal:  Int J Mol Sci       Date:  2022-08-10       Impact factor: 6.208

5.  Photocrosslinking of cDNA Display Molecules with Their Target Proteins as a New Strategy for Peptide Selection.

Authors:  Takuya Terai; Tomoyuki Koike; Naoto Nemoto
Journal:  Molecules       Date:  2020-03-24       Impact factor: 4.411

6.  Antibody bivalency improves antiviral efficacy by inhibiting virion release independently of Fc gamma receptors.

Authors:  Mehmet Sahin; Melissa M Remy; Benedict Fallet; Rami Sommerstein; Marianna Florova; Anna Langner; Katja Klausz; Tobias Straub; Mario Kreutzfeldt; Ingrid Wagner; Cinzia T Schmidt; Pauline Malinge; Giovanni Magistrelli; Shozo Izui; Hanspeter Pircher; J Sjef Verbeek; Doron Merkler; Matthias Peipp; Daniel D Pinschewer
Journal:  Cell Rep       Date:  2022-02-01       Impact factor: 9.423

Review 7.  Human immunology and immunotherapy: main achievements and challenges.

Authors:  Jezabel Varadé; Susana Magadán; África González-Fernández
Journal:  Cell Mol Immunol       Date:  2020-09-02       Impact factor: 22.096
  7 in total

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