| Literature DB >> 3152949 |
R Nygaard1, K S Bjerve, S Kolmannskog, P J Moe, F Wesenberg.
Abstract
Sixty-one children were examined for thyroid dysfunction as an adverse late effect after cessation of antileukemic treatment. The aim of the study was to contribute to clarifying which types of therapy can cause this endocrine disorder. Our treatment protocols do not include cranial irradiation as CNS prophylaxis, but we give relatively intensive intrathecal methotrexate treatment. The results indicate that this cytostatic regimen alone does not cause thyroid dysfunction as an adverse late effect.Entities:
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Year: 1988 PMID： 3152949 DOI： 10.3109/08880018809031249
Source DB: PubMed Journal: Pediatr Hematol Oncol ISSN： 0888-0018 Impact factor: 1.969