Literature DB >> 31528701

Hepatocytes prepare the soil for liver metastasis.

Jae W Lee1,2, Gregory L Beatty1,2.   

Abstract

The liver is the most common organ site of cancer metastasis. Molecular determinants of this organotropism, though, are poorly understood. We recently showed that hepatocytes regulate the formation of a "pro-metastatic" niche in the liver via their release of serum amyloid proteins.

Entities:  

Keywords:  Metastasis; hepatocytes; liver; pancreatic cancer; therapy

Year:  2019        PMID： 31528701      PMCID： PMC6736154          DOI： 10.1080/23723556.2019.1632686

Source DB:  PubMed          Journal:  Mol Cell Oncol        ISSN： 2372-3556


  10 in total

1.  Comments on hematogenous metastatic patterns in humans as revealed by autopsy.

Authors:  L Weiss
Journal:  Clin Exp Metastasis       Date:  1992-05       Impact factor: 5.150

2.  Cancer statistics, 2019.

Authors:  Rebecca L Siegel; Kimberly D Miller; Ahmedin Jemal
Journal:  CA Cancer J Clin       Date:  2019-01-08       Impact factor: 508.702

3.  Detection of early pancreatic ductal adenocarcinoma with thrombospondin-2 and CA19-9 blood markers.

Authors:  Jungsun Kim; William R Bamlet; Ann L Oberg; Kari G Chaffee; Greg Donahue; Xing-Jun Cao; Suresh Chari; Benjamin A Garcia; Gloria M Petersen; Kenneth S Zaret
Journal:  Sci Transl Med       Date:  2017-07-12       Impact factor: 17.956

4.  Regulation of Epithelial Plasticity Determines Metastatic Organotropism in Pancreatic Cancer.

Authors:  Maximilian Reichert; Basil Bakir; Leticia Moreira; Jason R Pitarresi; Karin Feldmann; Lauren Simon; Kensuke Suzuki; Ravikanth Maddipati; Andrew D Rhim; Anna M Schlitter; Mark Kriegsmann; Wilko Weichert; Matthias Wirth; Kathleen Schuck; Günter Schneider; Dieter Saur; Albert B Reynolds; Andres J Klein-Szanto; Burcin Pehlivanoglu; Bahar Memis; N Volkan Adsay; Anil K Rustgi
Journal:  Dev Cell       Date:  2018-06-18       Impact factor: 12.270

5.  IFNγ and CCL2 Cooperate to Redirect Tumor-Infiltrating Monocytes to Degrade Fibrosis and Enhance Chemotherapy Efficacy in Pancreatic Carcinoma.

Authors:  Kristen B Long; Whitney L Gladney; Graham M Tooker; Kathleen Graham; Joseph A Fraietta; Gregory L Beatty
Journal:  Cancer Discov       Date:  2016-02-19       Impact factor: 39.397

6.  Pancreatic cancer exosomes initiate pre-metastatic niche formation in the liver.

Authors:  Bruno Costa-Silva; Nicole M Aiello; Allyson J Ocean; Swarnima Singh; Haiying Zhang; Basant Kumar Thakur; Annette Becker; Ayuko Hoshino; Milica Tešić Mark; Henrik Molina; Jenny Xiang; Tuo Zhang; Till-Martin Theilen; Guillermo García-Santos; Caitlin Williams; Yonathan Ararso; Yujie Huang; Gonçalo Rodrigues; Tang-Long Shen; Knut Jørgen Labori; Inger Marie Bowitz Lothe; Elin H Kure; Jonathan Hernandez; Alexandre Doussot; Saya H Ebbesen; Paul M Grandgenett; Michael A Hollingsworth; Maneesh Jain; Kavita Mallya; Surinder K Batra; William R Jarnagin; Robert E Schwartz; Irina Matei; Héctor Peinado; Ben Z Stanger; Jacqueline Bromberg; David Lyden
Journal:  Nat Cell Biol       Date:  2015-05-18       Impact factor: 28.824

7.  Vitamin D receptor-mediated stromal reprogramming suppresses pancreatitis and enhances pancreatic cancer therapy.

Authors:  Mara H Sherman; Ruth T Yu; Dannielle D Engle; Ning Ding; Annette R Atkins; Herve Tiriac; Eric A Collisson; Frances Connor; Terry Van Dyke; Serguei Kozlov; Philip Martin; Tiffany W Tseng; David W Dawson; Timothy R Donahue; Atsushi Masamune; Tooru Shimosegawa; Minoti V Apte; Jeremy S Wilson; Beverly Ng; Sue Lynn Lau; Jenny E Gunton; Geoffrey M Wahl; Tony Hunter; Jeffrey A Drebin; Peter J O'Dwyer; Christopher Liddle; David A Tuveson; Michael Downes; Ronald M Evans
Journal:  Cell       Date:  2014-09-25       Impact factor: 41.582

8.  Focal Adhesion Kinase Regulates Hepatic Stellate Cell Activation and Liver Fibrosis.

Authors:  Xue-Ke Zhao; Lei Yu; Ming-Liang Cheng; Pulin Che; Yin-Ying Lu; Quan Zhang; Mao Mu; Hong Li; Li-Li Zhu; Juan-Juan Zhu; Meng Hu; Po Li; Yue-Dong Liang; Xin-Hua Luo; Yi-Ju Cheng; Zhi-Xiang Xu; Qiang Ding
Journal:  Sci Rep       Date:  2017-06-22       Impact factor: 4.379

9.  Hepatocytes direct the formation of a pro-metastatic niche in the liver.

Authors:  Jae W Lee; Meredith L Stone; Paige M Porrett; Stacy K Thomas; Chad A Komar; Joey H Li; Devora Delman; Kathleen Graham; Whitney L Gladney; Xia Hua; Taylor A Black; Austin L Chien; Krishna S Majmundar; Jeffrey C Thompson; Stephanie S Yee; Mark H O'Hara; Charu Aggarwal; Dong Xin; Abraham Shaked; Mingming Gao; Dexi Liu; Mitesh J Borad; Ramesh K Ramanathan; Erica L Carpenter; Ailing Ji; Maria C de Beer; Frederick C de Beer; Nancy R Webb; Gregory L Beatty
Journal:  Nature       Date:  2019-03-06       Impact factor: 49.962

10.  Serum Amyloid A Induces Inflammation, Proliferation and Cell Death in Activated Hepatic Stellate Cells.

Authors:  Sören V Siegmund; Monika Schlosser; Frank A Schildberg; Ekihiro Seki; Samuele De Minicis; Hiroshi Uchinami; Christian Kuntzen; Percy A Knolle; Christian P Strassburg; Robert F Schwabe
Journal:  PLoS One       Date:  2016-03-03       Impact factor: 3.240
  10 in total
  1 in total

1.  Inflammatory networks cultivate cancer cell metastasis to the liver.

Authors:  Jae W Lee; Gregory L Beatty
Journal:  Cell Cycle       Date:  2020-02-13       Impact factor: 4.534
  1 in total

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