Literature DB >> 315286

Occurrence of antibodies to single-stranded DNA in ANA negative patients.

C A Wasicek, P J Maddison, M Reichlin.   

Abstract

Five patients with clinical features of a connective tissue disease most suggestive of systemic lupus erythematosus were found to have a negative ANA by conventional screening at 1/20 dilution on mouse liver. However, significant titres of antibodies to single-stranded DNA were detected using a double antibody radioimmunoassay. Thus, certain patients have antibodies to DNA restricted to single-stranded determinants as detected by radioimmunoassay with single-stranded DNA as antigen and a negative ANA test.

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Year:  1979        PMID： 315286      PMCID： PMC1537813     

Source DB:  PubMed          Journal:  Clin Exp Immunol        ISSN： 0009-9104            Impact factor:   4.330


  8 in total

1.  Limited anti-DNA antibody specificity in systemic lupus erythematosus.

Authors:  R N Berzofsky; C A Dorsch; M B Stevens
Journal:  Arthritis Rheum       Date:  1977 Sep-Oct

2.  Iodination of nucleic acids in vitro.

Authors:  S L Commerford
Journal:  Biochemistry       Date:  1971-05-25       Impact factor: 3.162

3.  Antibodies to cytoplasmic antigens in lupus erythematosus. Serologic marker for systemic disease.

Authors:  T T Provost; A Razzaque; P J Maddison; M Reichlin
Journal:  Arthritis Rheum       Date:  1977 Nov-Dec

4.  Heterogeneity of RNA protein antigens reactive with sera of patients with systemic lupus erythematosus. Description of a cytoplasmic nonribosomal antigen.

Authors:  M Mattioli; M Reichlin
Journal:  Arthritis Rheum       Date:  1974 Jul-Aug

5.  Correlation of a precipitin reaction to an RNAprotein antigen and a low prevalence of nephritis in patients with systemic lupus erythematosus.

Authors:  M Reichlin; M Mattioli
Journal:  N Engl J Med       Date:  1972-04-27       Impact factor: 91.245

6.  Antibodies to native and denatured deoxyribonucleic acid in systemic lupus erythematosus.

Authors:  R Arana; M Seligmann
Journal:  J Clin Invest       Date:  1967-11       Impact factor: 14.808

7.  Immunology of DNA. III. Crithidia luciliae, a simple substrate for the determination of anti-dsDNA with the immunofluorescence technique.

Authors:  L A Aarden; E R de Groot; T E Feltkamp
Journal:  Ann N Y Acad Sci       Date:  1975-06-30       Impact factor: 5.691

8.  Nuclear fluorescence employing antinucleoside immunoglobulins.

Authors:  W J Klein; S M Beiser; B F Erlanger
Journal:  J Exp Med       Date:  1967-01-01       Impact factor: 14.307
  8 in total
  2 in total

Review 1.  Ro (SSA) and La (SSB) antibodies.

Authors:  E L Alexander; T T Provost
Journal:  Springer Semin Immunopathol       Date:  1981

2.  Clinical and serological differences between systemic lupus erythematosus patients with antibodies to Ro versus patients with antibodies to Ro and La.

Authors:  C A Wasicek; M Reichlin
Journal:  J Clin Invest       Date:  1982-04       Impact factor: 14.808
  2 in total

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