Literature DB >> 31528068

Acute venous thromboembolism in Indian patients of isolated proximal femur fractures.

Rahul Saket1, Sameer Aggarwal1, Vishal Kumar1, Prasoon Kumar1, Sandeep Patel1.   

Abstract

INTRODUCTION: Venous Thromboembolism (VTE) has a variable incidence in trauma patients and fatal embolism can be the very first manifestation. Proximal femur fractures result from high velocity trauma in younger age groups and could require prolonged immobilisation, which is associated with increased risk of VTE. Therefore we sought to determine the occurrance of VTE in patients with proximal femur fractures.
OBJECTIVES: The present study was initiated to assess the occurrance of deep vein thrombosis (DVT) or pulmonary embolism in isolated proximal femur fractures and identify the requirement of routine thromboprophylaxis in such patients.
METHODS: It was a prospective study conducted over a period of one and a half years. All patients, presenting with isolated proximal femur fractures were included. Patients having any other known risk factors for DVT were excluded, so that the proximal femur fracture remained their only acquired risk for DVT. All the patients were evaluated clinically and with help of diagnostic modalities like Color Doppler with compression ultrasound, D-dimer assays and CT venogram, if indicated. Patients were followed up till 8 weeks post-operatively.
RESULTS: A total of 66 patients with fractures of proximal femur were assessed, out of which there were 42 males with mean age of 48.1 years and 24 females with mean age of 58.3 years. A total of 9 cases of radiologically proved DVT were observed. Clinical DVT was seen in 5 of these cases (54%). Complete resolution of thrombus was noted in all the patients, evaluated by Color Doppler at 6 weeks, post diagnosis. Although the majority of the cases (6) occurred in patients beyond 50 years of age, this was not statistically significant.
CONCLUSION: DVT is common in patients with proximal femur fractures and the provision for screening both clinically and radiologically, should be made routine in all such patients. In case of delay in surgery and patient being bed ridden, we recommend thromboprophylaxis in this subset of trauma patients.

Entities:  

Keywords:  DVT; Deep vein thrombosis; PE; Proximal femur fractures; Pulmonary Embolism; Thromboprophylaxis; VTE; Venous thromboembolism

Year:  2019        PMID: 31528068      PMCID: PMC6739242          DOI: 10.1016/j.jcot.2019.02.016

Source DB:  PubMed          Journal:  J Clin Orthop Trauma        ISSN: 0976-5662


  31 in total

1.  Mechanical prophylaxis against deep-vein thrombosis after pelvic and acetabular fractures.

Authors:  J P Stannard; R S Riley; M D McClenney; R R Lopez-Ben; D A Volgas; J E Alonso
Journal:  J Bone Joint Surg Am       Date:  2001-07       Impact factor: 5.284

2.  Deep-vein thrombosis in high-energy skeletal trauma despite thromboprophylaxis.

Authors:  J P Stannard; A K Singhania; R R Lopez-Ben; E R Anderson; R C Farris; D A Volgas; G R McGwin; J E Alonso
Journal:  J Bone Joint Surg Br       Date:  2005-07

3.  Deep-vein thrombosis rates after major orthopedic surgery in Asia. An epidemiological study based on postoperative screening with centrally adjudicated bilateral venography.

Authors:  F Piovella; C-J Wang; H Lu; K Lee; L H Lee; W C Lee; A G G Turpie; A S Gallus; A Planès; R Passera; A Rouillon
Journal:  J Thromb Haemost       Date:  2005-12       Impact factor: 5.824

4.  Incidence and natural history of deep-vein thrombosis after total knee arthroplasty. A prospective, randomised study.

Authors:  Young-Hoo Kim; J S Kim
Journal:  J Bone Joint Surg Br       Date:  2002-05

5.  Greenfield filter prophylaxis of pulmonary embolism in patients undergoing surgery for acetabular fracture.

Authors:  L X Webb; P T Rush; S B Fuller; J W Meredith
Journal:  J Orthop Trauma       Date:  1992       Impact factor: 2.512

6.  Deep vein thrombosis after total hip arthroplasty in Indian patients with and without enoxaparin.

Authors:  V Jain; A K Dhal; B K Dhaon; G Pradhan
Journal:  J Orthop Surg (Hong Kong)       Date:  2004-12       Impact factor: 1.118

7.  The incidence of deep vein thrombosis in elderly Chinese suffering hip fracture is low without prophylaxis: a prospective study using serial duplex ultrasound.

Authors:  Y K Chan; K Y Chiu; S Wk Cheng; P Ho
Journal:  J Orthop Surg (Hong Kong)       Date:  2004-12       Impact factor: 1.118

8.  Incidence and natural history of deep-vein thrombosis after total hip arthroplasty. A prospective and randomised clinical study.

Authors:  Young-Hoo Kim; S H Oh; J S Kim
Journal:  J Bone Joint Surg Br       Date:  2003-07

9.  Incidence and risk factors for development of venous thromboembolism in Indian patients undergoing major orthopaedic surgery: results of a prospective study.

Authors:  V Bagaria; N Modi; A Panghate; S Vaidya
Journal:  Postgrad Med J       Date:  2006-02       Impact factor: 2.401

10.  Pulmonary thromboembolism in Asians/Pacific Islanders in the United States: analysis of data from the National Hospital Discharge Survey and the United States Bureau of the Census.

Authors:  Paul D Stein; Fadi Kayali; Ronald E Olson; Creagh E Milford
Journal:  Am J Med       Date:  2004-04-01       Impact factor: 4.965

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