C Van Heugten1, S Köhler2, M Francke3, Y Bol4. 1. Maastricht University Medical Center, School for Mental Health and Neuroscience, Maastricht, the Netherlands; Maastricht University, Department of Neuropsychology & Psychopharmacology, Maastricht, the Netherlands; Limburg Brain Injury Center, Maastricht University, Maastricht, the Netherlands. 2. Maastricht University Medical Center, School for Mental Health and Neuroscience, Maastricht, the Netherlands. 3. Zuyderland Medical Centre, Department of Clinical and Medical Psychology, Sittard-Geleen, Heerlen, the Netherlands. 4. Zuyderland Medical Centre, Department of Clinical and Medical Psychology, Sittard-Geleen, Heerlen, the Netherlands. Electronic address: y.bol@zuyderland.nl.
Abstract
OBJECTIVES: To investigate the direct, mediated and moderated relationships between executive functioning, coping and depressive symptoms in patients with multiple sclerosis (MS). METHODS: Cross-sectional cohort study of routine follow-up visits, including a standardized (neuro)psychological evaluation of 68 MS patients. Coping was measured with the Coping Inventory for Stressful Situations; Depressive symptoms with the subscale depression of the Hospital Anxiety and Depression Scale. Cognitive tests were reduced to a single 'executive function' factor by means of confirmatory factor analysis. Path analyses tested mediating and moderating effects of coping on the relation between executive functioning and depressive symptoms. RESULTS: Consistently, the executive functioning factor was not related to task-oriented and emotion-oriented coping. Better executive functioning, however, and less reliance on avoidance coping, was related to more depressive symptoms. Testing of the mediating path showed that executive dysfunctioning was indeed significantly related to more depressive symptoms by less reliance on avoidance coping. There was no additional direct effect of executive functioning on depressive symptoms and also no moderating effect of any coping style on the association between cognition and depressive symptoms. CONCLUSION: Our findings suggest that task-oriented and emotion-oriented coping do not influence the relationship between executive functioning and depression in MS patients, but their mental health might benefit from more reliance on avoidance coping.
OBJECTIVES: To investigate the direct, mediated and moderated relationships between executive functioning, coping and depressive symptoms in patients with multiple sclerosis (MS). METHODS: Cross-sectional cohort study of routine follow-up visits, including a standardized (neuro)psychological evaluation of 68 MSpatients. Coping was measured with the Coping Inventory for Stressful Situations; Depressive symptoms with the subscale depression of the Hospital Anxiety and Depression Scale. Cognitive tests were reduced to a single 'executive function' factor by means of confirmatory factor analysis. Path analyses tested mediating and moderating effects of coping on the relation between executive functioning and depressive symptoms. RESULTS: Consistently, the executive functioning factor was not related to task-oriented and emotion-oriented coping. Better executive functioning, however, and less reliance on avoidance coping, was related to more depressive symptoms. Testing of the mediating path showed that executive dysfunctioning was indeed significantly related to more depressive symptoms by less reliance on avoidance coping. There was no additional direct effect of executive functioning on depressive symptoms and also no moderating effect of any coping style on the association between cognition and depressive symptoms. CONCLUSION: Our findings suggest that task-oriented and emotion-oriented coping do not influence the relationship between executive functioning and depression in MSpatients, but their mental health might benefit from more reliance on avoidance coping.
Authors: Carmen Concerto; Alessandro Rodolico; Alessia Ciancio; Christian Messina; Antimo Natale; Ludovico Mineo; Fortunato Battaglia; Eugenio Aguglia Journal: Int J Environ Res Public Health Date: 2021-12-25 Impact factor: 3.390
Authors: Maarten Van Herck; Yvonne M J Goërtz; Sarah Houben-Wilke; Felipe V C Machado; Roy Meys; Jeannet M Delbressine; Anouk W Vaes; Chris Burtin; Rein Posthuma; Frits M E Franssen; Bita Hajian; Herman Vijlbrief; Yvonne Spies; Alex J van 't Hul; Daisy J A Janssen; Martijn A Spruit Journal: J Med Internet Res Date: 2021-09-21 Impact factor: 5.428