Saliha Belmonte1, Pedro Montoya1, Ana M González-Roldán1, Inmaculada Riquelme2. 1. University Institute of Health Sciences Research (IUNICS-IdISPa), University of the Balearic Islands, Palma de Mallorca, Spain. 2. University Institute of Health Sciences Research (IUNICS-IdISPa), University of the Balearic Islands, Palma de Mallorca, Spain; Department of Nursing and Physiotherapy, University of the Balearic Islands, Palma de Mallorca, Spain. Electronic address: inma.riquelme@uib.es.
Abstract
Sensory and cognitive deficits are common comorbidities in children with cerebral palsy. This observational study examines if brain processing of affective information is also altered in children with cerebral palsy (CP) in comparison with typically developing peers (TDP). METHODS: Evoked-related potentials were recorded in 15 children with CP (age = 11.27 ± 4.53 yr, 6 girls) and 14 TDP (age = 10.14 ± 4.29 yr, 5 girls) when viewing pleasant, unpleasant and neutral pictures. The subjective perception of valence and arousal of each one of the pictures was examined. RESULTS: Children with CP showed a significant amplitude reduction of evoked potentials in the occipital region to the affective stimuli in early brain processing latencies (P100 and N200; all F > 2.9, all p < .05). Children with CP rated pictures with affective content (pleasant and unpleasant) as less arousing (F(2.25) = 46.71, p < .001), and neutral pictures as more pleasant, than their TDP (F(2.25) = 75.56, p < .001). CONCLUSION: The pictures with emotional content produce less activation, both at the behavioral and brain processing levels in children with CP. These differences were found in early latencies of brain processing which could be related to alterations in the detection of emotionally relevant stimuli.
Sensory and cognitive deficits are common comorbidities in children with cerebral palsy. This observational study examines if brain processing of affective information is also altered in children with cerebral palsy (CP) in comparison with typically developing peers (TDP). METHODS: Evoked-related potentials were recorded in 15 children with CP (age = 11.27 ± 4.53 yr, 6 girls) and 14 TDP (age = 10.14 ± 4.29 yr, 5 girls) when viewing pleasant, unpleasant and neutral pictures. The subjective perception of valence and arousal of each one of the pictures was examined. RESULTS:Children with CP showed a significant amplitude reduction of evoked potentials in the occipital region to the affective stimuli in early brain processing latencies (P100 and N200; all F > 2.9, all p < .05). Children with CP rated pictures with affective content (pleasant and unpleasant) as less arousing (F(2.25) = 46.71, p < .001), and neutral pictures as more pleasant, than their TDP (F(2.25) = 75.56, p < .001). CONCLUSION: The pictures with emotional content produce less activation, both at the behavioral and brain processing levels in children with CP. These differences were found in early latencies of brain processing which could be related to alterations in the detection of emotionally relevant stimuli.