Ryan McGrath1, Brenda M Vincent2, Kyle J Hackney3, Soham Al Snih4, James Graham5, Laura Thomas6, Diane K Ehlers7, Brian C Clark8,9,10. 1. Department of Health, Nutrition, and Exercise Sciences, North Dakota State University, NDSU Dept. 2620, PO Box 6050, Fargo, ND, 58108-6050, USA. ryan.mcgrath@ndsu.edu. 2. Department of Statistics, North Dakota State University, Fargo, ND, USA. 3. Department of Health, Nutrition, and Exercise Sciences, North Dakota State University, NDSU Dept. 2620, PO Box 6050, Fargo, ND, 58108-6050, USA. 4. Division of Rehabilitation Sciences, University of Texas Medical Branch, Galveston, TX, USA. 5. Department of Occupational Therapy, Colorado State University, Fort Collins, CO, USA. 6. Department of Psychology, North Dakota State University, Fargo, ND, USA. 7. Department of Neurological Sciences, University of Nebraska Medical Center, Omaha, NE, USA. 8. Ohio Musculoskeletal and Neurological Institute, Ohio University, Athens, OH, USA. 9. Department of Geriatric Medicine, Ohio University, Athens, OH, USA. 10. Department of Biomedical Sciences, Ohio University, Athens, OH, USA.
Abstract
BACKGROUND: Discovering how certain health factors contribute to functional declines may help to promote successful aging. AIMS: To determine the independent and joint associations of handgrip strength (HGS) and cognitive function with instrumental activities of daily living (IADL) and activities of daily living (ADL) disability decline in aging Americans. METHODS: Data from 18,391 adults aged 50 years and over who participated in at least one wave of the 2006-2014 waves of the Health and Retirement Study were analyzed. A hand-held dynamometer assessed HGS and cognitive functioning was examined with a modified version of the Telephone Interview of Cognitive Status. IADL and ADL abilities were self-reported. Participants were stratified into four distinct groups based on their HGS and cognitive function status. Separate covariate-adjusted multilevel models were conducted for the analyses. RESULTS: Participants who were weak, had a cognitive impairment, and had both weakness and a cognitive impairment had 1.70 (95% confidence interval (CI) 1.57-1.84), 1.97 (CI 1.74-2.23), and 3.13 (CI 2.73-3.59) greater odds for IADL disability decline, respectively, and 2.26 (CI 2.03-2.51), 1.26 (CI 1.05-1.51), and 4.48 (CI 3.72-5.39) greater odds for ADL disability decline, respectively. DISCUSSION: HGS and cognitive functioning were independently and jointly associated with IADL and ADL disability declines. Individuals with both weakness and cognitive impairment demonstrated substantially higher odds for functional decline than those with either risk factor alone. CONCLUSIONS: Including measures of both HGS and cognitive functioning in routine geriatric assessments may help to identify those at greatest risk for declining functional capacity.
BACKGROUND: Discovering how certain health factors contribute to functional declines may help to promote successful aging. AIMS: To determine the independent and joint associations of handgrip strength (HGS) and cognitive function with instrumental activities of daily living (IADL) and activities of daily living (ADL) disability decline in aging Americans. METHODS: Data from 18,391 adults aged 50 years and over who participated in at least one wave of the 2006-2014 waves of the Health and Retirement Study were analyzed. A hand-held dynamometer assessed HGS and cognitive functioning was examined with a modified version of the Telephone Interview of Cognitive Status. IADL and ADL abilities were self-reported. Participants were stratified into four distinct groups based on their HGS and cognitive function status. Separate covariate-adjusted multilevel models were conducted for the analyses. RESULTS:Participants who were weak, had a cognitive impairment, and had both weakness and a cognitive impairment had 1.70 (95% confidence interval (CI) 1.57-1.84), 1.97 (CI 1.74-2.23), and 3.13 (CI 2.73-3.59) greater odds for IADL disability decline, respectively, and 2.26 (CI 2.03-2.51), 1.26 (CI 1.05-1.51), and 4.48 (CI 3.72-5.39) greater odds for ADL disability decline, respectively. DISCUSSION: HGS and cognitive functioning were independently and jointly associated with IADL and ADL disability declines. Individuals with both weakness and cognitive impairment demonstrated substantially higher odds for functional decline than those with either risk factor alone. CONCLUSIONS: Including measures of both HGS and cognitive functioning in routine geriatric assessments may help to identify those at greatest risk for declining functional capacity.
Entities:
Keywords:
Dementia; Epidemiology; Geriatrics; Muscle strength; Nervous system
Authors: Kelly Parker; Brenda Vincent; Yeong Rhee; Bong-Jin Choi; Sheria G Robinson-Lane; Jeremy M Hamm; Lukus Klawitter; Donald A Jurivich; Ryan McGrath Journal: Aging Clin Exp Res Date: 2021-09-15 Impact factor: 3.636
Authors: María Aliño-Dies; Joan Vicent Sánchez-Ortí; Patricia Correa-Ghisays; Vicent Balanzá-Martínez; Joan Vila-Francés; Gabriel Selva-Vera; Paulina Correa-Estrada; Jaume Forés-Martos; Constanza San-Martín Valenzuela; Manuel Monfort-Pañego; Rosa Ayesa-Arriola; Miguel Ruiz-Veguilla; Benedicto Crespo-Facorro; Rafael Tabarés-Seisdedos Journal: Front Psychol Date: 2020-11-25