Rodney De Palma1, Crochan J O'Sullivan2, Magnus Settergren2. 1. Heart and Vascular Theme, Karolinska University Hospital and Karolinska Institutet, SE-171 76, Stockholm, Sweden. rodney_de_palma@icloud.com. 2. Heart and Vascular Theme, Karolinska University Hospital and Karolinska Institutet, SE-171 76, Stockholm, Sweden.
Abstract
PURPOSE OF REVIEW: The goal was to evaluate published data on the incidence, diagnosis, and management of symptomatic combined mitral and aortic valvular disease. Furthermore, to identify the role of treatment using contemporary transcatheter techniques. RECENT FINDINGS: Up to a quarter of symptomatic adult valvular disease is caused by multiple left-sided valvular lesions. The etiologic spectrum of this combined disease has shifted from rheumatic to degenerative. Both presentation and diagnosis of lesions are modified compared with isolated disease. Based upon narrative review, there are only limited observational experiences, insufficient to provide robust guidance. These data, however, indicate the feasibility of interventions such as transcatheter aortic valve replacement and edge-to-edge mitral valve repair to treat such disease and mitigate the risks of open surgery. Combined aortic and mitral valve disease is commonly encountered. There is a role for transcatheter interventions based on limited data; however, more research is needed.
PURPOSE OF REVIEW: The goal was to evaluate published data on the incidence, diagnosis, and management of symptomatic combined mitral and aortic valvular disease. Furthermore, to identify the role of treatment using contemporary transcatheter techniques. RECENT FINDINGS: Up to a quarter of symptomatic adult valvular disease is caused by multiple left-sided valvular lesions. The etiologic spectrum of this combined disease has shifted from rheumatic to degenerative. Both presentation and diagnosis of lesions are modified compared with isolated disease. Based upon narrative review, there are only limited observational experiences, insufficient to provide robust guidance. These data, however, indicate the feasibility of interventions such as transcatheter aortic valve replacement and edge-to-edge mitral valve repair to treat such disease and mitigate the risks of open surgery. Combined aortic and mitral valve disease is commonly encountered. There is a role for transcatheter interventions based on limited data; however, more research is needed.
Authors: Richard Lee; Shuang Li; J Scott Rankin; Sean M O'Brien; James S Gammie; Eric D Peterson; Patrick M McCarthy; Fred H Edwards Journal: Ann Thorac Surg Date: 2011-03 Impact factor: 4.330
Authors: Vuyisile T Nkomo; Julius M Gardin; Thomas N Skelton; John S Gottdiener; Christopher G Scott; Maurice Enriquez-Sarano Journal: Lancet Date: 2006-09-16 Impact factor: 79.321
Authors: A Marc Gillinov; Eugene H Blackstone; Delos M Cosgrove; Jennifer White; Paul Kerr; Antonino Marullo; Patrick M McCarthy; Bruce W Lytle Journal: J Thorac Cardiovasc Surg Date: 2003-06 Impact factor: 5.209
Authors: Bernard Iung; Gabriel Baron; Eric G Butchart; François Delahaye; Christa Gohlke-Bärwolf; Olaf W Levang; Pilar Tornos; Jean-Louis Vanoverschelde; Frank Vermeer; Eric Boersma; Philippe Ravaud; Alec Vahanian Journal: Eur Heart J Date: 2003-07 Impact factor: 29.983
Authors: Bruce J Leavitt; Yvon R Baribeau; Anthony W DiScipio; Cathy S Ross; Reed D Quinn; Elaine M Olmstead; Donato Sisto; Donald S Likosky; Richard P Cochran; Robert A Clough; Richard A Boss; Robert S Kramer; Gerald T O'Connor Journal: Circulation Date: 2009-09-15 Impact factor: 29.690