Literature DB >> 3151963

Model structure of a fragment of biological knowledge (cell motility).

J Doroszewski1, A Delegacz.   

Abstract

The aim of the study is to contribute to a better understanding of some aspects of the structure of biological knowledge and to make clearer to what extent the methods of reasoning may be useful in this field when only qualitative information is available. A fragment of biological knowledge (theory of cell motility) is analysed from the logicomethodological point of view as a coherent system and the possibility of its formal representation is investigated. The analysis is based on distinguishing the main objects and their features (attributes) of which a given piece of knowledge is composed and on the values which these features may display. The features are interconnected by relations (in which various number of arguments appear) and these relations constitute the main (general, higher level) laws of a given fragment of knowledge (theory). Values of attributes are also mutually connected and these relations correspond to the detailed (lower level) laws. A computer system (in which Prolog language was used) enables to perform inference operations of progressive as well as regressive type. The main categories of reasoning procedures are described and illustrated by examples, namely a) search for conclusions which may be confronted with the actual knowledge in order to verify the system as a whole, b) formation of working hypotheses in the process of their empirical verification and explanation of facts and laws. The problem of development and modification of the system is also discussed.

Mesh:

Year:  1988        PMID: 3151963     DOI: 10.1007/bf00154136

Source DB:  PubMed          Journal:  Acta Biotheor        ISSN: 0001-5342            Impact factor:   1.774


  3 in total

1.  Locomotion of granulocytes on an inclined plane.

Authors:  J Doroszewski; K Lewandowska; W Wierzbicki
Journal:  Acta Physiol Pol       Date:  1986 Mar-Apr

2.  Computer programs as theories in biology.

Authors:  D Partridge; P D Lopez; V S Johnston
Journal:  J Theor Biol       Date:  1984-06-21       Impact factor: 2.691

3.  Adhesion and locomotion of granulocytes under flow conditions.

Authors:  J Doroszewski; A Kiwała
Journal:  J Cell Sci       Date:  1988-06       Impact factor: 5.285

  3 in total

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