Literature DB >> 31517710

Surgical approaches to hemophilic arthropathy.

E Carlos Rodriguez-Merchan1.   

Abstract

: The role of the orthopedic surgeon is to use invasive and/or surgical methods to treat the musculoskeletal disorders suffered by persons with hemophilia, always within the context of a multidisciplinary team. Muscle hematomas must be diagnosed as early as possible and be subjected to continuous treatment until full resolution, as they are associated with the risk of severe complications (compartment syndromes and pseudotumors). Arthrocentesis (extraction of intra-articular blood) is recommended in cases of acute and profuse hemarthrosis. Synovectomy is mandatory in the case of synovitis. Radiosynovectomy plays a key role as it has been shown to reduce bleeding by 65%. Our department uses Yttrium-90 in knees and Rhenium-186 in elbows and ankles. Radiosynovectomy is our treatment of choice for synovitis whereas arthroscopic synovectomy is resorted to as second-line treatment. Total knee replacement (TKR) has shown itself to be effective for treating severe hemophilic arthropathy, although the infection risk in patients with hemophilia is higher than in patients with osteoarthritis (1-2 vs. 7%).

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Year:  2019        PMID: 31517710     DOI: 10.1097/MBC.0000000000000824

Source DB:  PubMed          Journal:  Blood Coagul Fibrinolysis        ISSN: 0957-5235            Impact factor:   1.276


  4 in total

Review 1.  Pathological mechanism of joint destruction in haemophilic arthropathy.

Authors:  Haijia Zhu; Yilin Meng; Peijian Tong; Shanxing Zhang
Journal:  Mol Biol Rep       Date:  2020-12-08       Impact factor: 2.316

2.  Postoperative bleeding complications in patients with hemophilia undergoing major orthopedic surgery: A prospective multicenter observational study.

Authors:  Brendan Kleiboer; Marcus A Layer; Lorraine A Cafuir; Adam Cuker; Miguel Escobar; M Elaine Eyster; Eric Kraut; Andrew D Leavitt; Steven R Lentz; Doris Quon; Margaret V Ragni; Dianne Thornhill; Michael Wang; Nigel S Key; Tyler W Buckner
Journal:  J Thromb Haemost       Date:  2022-02-08       Impact factor: 5.824

3.  The Application of Focused Medium-Energy Extracorporeal Shockwave Therapy in Hemophilic A Arthropathy.

Authors:  Wan-Shan Lo; Jiunn-Ming Sheen; Yu-Chieh Chen; Kuan-Ting Wu; Lin-Yi Wang; Yiu-Chung Lau; Chih-Cheng Hsiao; Jih-Yang Ko
Journal:  Healthcare (Basel)       Date:  2022-02-11

4.  Artificial Intelligence Algorithm-Based Magnetic Resonance Imaging to Evaluate the Effect of Radiation Synovectomy for Hemophilic Arthropathy.

Authors:  Heng Zhang; Shukai Duan; Wei Xiao; Xinyue Yang; Shenglin Li
Journal:  Contrast Media Mol Imaging       Date:  2022-03-19       Impact factor: 3.161

  4 in total

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