Literature DB >> 31514986

Three new bioactive flavonoid glycosides from Viscum album.

Jia-Kun Dai1, Duo Cao2, Cui-Hua Li3, Jing Gao3, Meng-Qing Li3, Na Fan4, Ya-Hui Wei5, Zheng-Liang Sun6, Meng-Yang Hou7.   

Abstract

Two new flavonoid glycosides, named viscumneoside XII (1), and viscumneoside XIII (2); a new dihydrogen flavonoid glycoside product named viscumneoside XIV (3), were isolated from the aerial part of Viscum album, along with seven known compounds (4-10). Their structures were identified by analysis of spectroscopic data. In addition, cytotoxicity assay showed that 1, 2 and 3 possessed significant inhibitory activities against C6, A549 and MDA-MB-231 (the inhibition rate arrived about 50%, 70% and 74% respectively with IC50 ≤ 60.00 μmol·L-1), while the inhibition of TF-1 and Hela was not significant.
Copyright © 2019 China Pharmaceutical University. Published by Elsevier B.V. All rights reserved.

Entities:  

Keywords:  Cytotoxic activities; Flavonoid glycosides; Viscum album

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Year:  2019        PMID: 31514986     DOI: 10.1016/S1875-5364(19)30076-7

Source DB:  PubMed          Journal:  Chin J Nat Med        ISSN: 1875-5364


  1 in total

1.  Antiamylase, Antilipase, Antimicrobial, and Cytotoxic Activity of Nonea obtusifolia (Willd.) DC. from Palestine.

Authors:  Nidal Jaradat; Murad N Abualhasan; Mohammad Qadi; Linda Issa; Ahmad Mousa; Fathia Allan; Mohammad Hindi; Zaid Alhrezat
Journal:  Biomed Res Int       Date:  2020-12-01       Impact factor: 3.411

  1 in total

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