| Literature DB >> 31514986 |
Jia-Kun Dai1, Duo Cao2, Cui-Hua Li3, Jing Gao3, Meng-Qing Li3, Na Fan4, Ya-Hui Wei5, Zheng-Liang Sun6, Meng-Yang Hou7.
Abstract
Two new flavonoid glycosides, named viscumneoside XII (1), and viscumneoside XIII (2); a new dihydrogen flavonoid glycoside product named viscumneoside XIV (3), were isolated from the aerial part of Viscum album, along with seven known compounds (4-10). Their structures were identified by analysis of spectroscopic data. In addition, cytotoxicity assay showed that 1, 2 and 3 possessed significant inhibitory activities against C6, A549 and MDA-MB-231 (the inhibition rate arrived about 50%, 70% and 74% respectively with IC50 ≤ 60.00 μmol·L-1), while the inhibition of TF-1 and Hela was not significant.Entities:
Keywords: Cytotoxic activities; Flavonoid glycosides; Viscum album
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Year: 2019 PMID: 31514986 DOI: 10.1016/S1875-5364(19)30076-7
Source DB: PubMed Journal: Chin J Nat Med ISSN: 1875-5364