[The monitoring of sensitivity of natural strains and clinical isolates of yeast fungus to anti-mycotics.]

The disc diffusion technique was applied to test sensitivity to anti-mycotics of 15 strains of fungi genus Candida separated from natural substrates and 25 clinical isolates. The fungi were of species C. albicans, C. glabrata, C. guilliermondii, C. parapsilosis, C. tropicalis.The high sensitivity of clinical isolates to Fluconazole, Nystatin, Сlotrimazole, Itraconazole, Amphotericin Bwas established, except strains C. glabrata 5 and C. tropicalis 4 demonstrating average level of sensitivity. The high sensitivity to anti-mycotics of strains separated from natural samples was demonstrated except 4 resistant strains C. parapsilosis. It can be supposed that up to one forth of natural strains of fungi genus Candida can have resistance to antibiotics, bringing to various forms of mycotic affections.