Literature DB >> 31502185

Ethnopharmacology, Phytochemistry, Pharmacology, Toxicology and Clinical Applications of Radix Astragali.

Chun-Hong Zhang1, Xiao Yang2, Jing-Ran Wei2, Na-Mu-Han Chen1, Jian-Ping Xu1, Ya-Qiong Bi3, Min Yang1, Xue Gong1, Zi-Yan Li1, Kai Ren1, Qi-Heng Han1, Lei Zhang2, Xue Li2, Ming-Yue Ji1, Cong-Cong Wang1, Min-Hui Li4,5.   

Abstract

Radix Astragali (RA), a traditional Chinese medicine from the dried root of Astragalus species, is widely distributed throughout the temperate regions of the world. The major bioactive constituents of RA are triterpene glycosides, flflavonoids, saponins, and alkaloids, and these compounds mostly exert pharmacological activities on the cardiovascular, immune, respiratory, and hepatic systems. This review summarizes the recent studies on RA and provides a comprehensive summary regarding the status of resources, ethnopharmacology, phytochemistry, pharmacology, toxicology, clinical application, and patent release of RA. We hope this review can provide a guidance for further development of therapeutic agents from RA.

Entities:  

Keywords:  Radix Astragali; clinical application; ethnopharmacology; pharmacology; phytochemistry; review

Year:  2019        PMID: 31502185     DOI: 10.1007/s11655-019-3032-8

Source DB:  PubMed          Journal:  Chin J Integr Med        ISSN: 1672-0415            Impact factor:   1.978


  9 in total

Review 1.  Astragalus polysaccharide: a review of its immunomodulatory effect.

Authors:  Chun-Xiao Li; Ying Liu; Yu-Zhen Zhang; Jing-Chun Li; Jiang Lai
Journal:  Arch Pharm Res       Date:  2022-06-17       Impact factor: 4.946

2.  RRLC-QTOF/MS-Based Metabolomics Reveal the Mechanism of Chemical Variations and Transformations of Astragali Radix as a Result of the Roasting Process.

Authors:  Yang Li; Shenhui Huang; Jie Sun; Weiping Duan; Cunyu Li; Guoping Peng; Yunfeng Zheng
Journal:  Front Chem       Date:  2022-05-05       Impact factor: 5.545

Review 3.  Zebrafish as a Useful Model to Study Oxidative Stress-Linked Disorders: Focus on Flavonoids.

Authors:  Francesco Abbate; Alessandro Maugeri; Rosaria Laurà; Maria Levanti; Michele Navarra; Santa Cirmi; Antonino Germanà
Journal:  Antioxidants (Basel)       Date:  2021-04-25

4.  Clinical Efficacy and Safety of Traditional Medicine Preparations Combined With Chemotherapy for Advanced Pancreatic Cancer: A Systematic Review and Meta-Analysis.

Authors:  Jiaqi Hu; Juling Jiang; Rui Liu; Mengqi Cheng; Guanghui Zhu; Shulin He; Bolun Shi; Yuwei Zhao; Zhongning He; Huibo Yu; Xing Zhang; Honggang Zheng; Baojin Hua
Journal:  Front Oncol       Date:  2022-02-23       Impact factor: 6.244

5.  Quality Control of Radix Astragali (The Root of Astragalus membranaceus var. mongholicus) Along Its Value Chains.

Authors:  Yaqiong Bi; Haiying Bao; Chunhong Zhang; Ruyu Yao; Minhui Li
Journal:  Front Pharmacol       Date:  2020-12-04       Impact factor: 5.810

6.  The "whole ingredients extract" of Astragali Radix improves the symptoms of dextran sulfate sodium-induced ulcerative colitis in mice through systemic immunomodulation.

Authors:  Ke-Gang Linghu; Qiushuo Ma; Shi-Hang Xiong; Mingming Zhao; Qiling Chen; Wen Xu; Meiwan Chen; Jian-Ye Zhang; Yuanjia Hu; Wei Xu; Hua Yu
Journal:  Chin Med       Date:  2022-09-15       Impact factor: 4.546

Review 7.  Medicinal and edible plants in the treatment of dyslipidemia: advances and prospects.

Authors:  Ying Hu; Xingjuan Chen; Mu Hu; Dongwei Zhang; Shuo Yuan; Ping Li; Ling Feng
Journal:  Chin Med       Date:  2022-09-29       Impact factor: 4.546

Review 8.  Natural Plant Extracts and Compounds for Rheumatoid Arthritis Therapy.

Authors:  Xiangyu Zhao; Young-Rok Kim; Yunhui Min; Yaping Zhao; Kyoungtag Do; Young-Ok Son
Journal:  Medicina (Kaunas)       Date:  2021-03-15       Impact factor: 2.430

9.  Effects of Physical Properties and Processing Methods on Astragaloside IV and Flavonoids Content in Astragali radix.

Authors:  Mei-Yin Chien; Chih-Min Yang; Chao-Hsiang Chen
Journal:  Molecules       Date:  2022-01-17       Impact factor: 4.411

  9 in total

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