| Literature DB >> 31499735 |
Hai Jun Hu1,2, Xu Pu Yuan1,3, Li Hong Huang1, Chuang Xia Huang1.
Abstract
In this paper, by taking full consideration of demographics, transfer from infectious to sus-ceptible and contact heterogeneity of the individuals, we construct an improved Susceptible-Infected-Removed-Susceptible (SIRS) epidemic model on complex heterogeneous networks. Using the next generation matrix method, we obtain the basic reproduction number $\mathcal{R}_0$ which is a critical value and used to measure the dynamics of epidemic diseases. More specifically, if $\mathcal{R}_0$ < 1, then the disease-free equilibrium is globally asymptotically stable; if $\mathcal{R}_0$ > 1, then there exists a unique endemic equilib-rium and the permanence of the disease is shown in detail. By constructing an appropriate Lyapunov function, the global stability of the endemic equilibrium is proved as well under some conditions. Moreover, the effects of three major immunization strategies are investigated. Finally, some numerical simulations are carried out to demonstrate the correctness and validness of the theoretical results.Entities:
Keywords: SIRS model; basic reproduction number; covariance driven; global dynamics; heterogeneous network; immunization strategy
Year: 2019 PMID: 31499735 DOI: 10.3934/mbe.2019286
Source DB: PubMed Journal: Math Biosci Eng ISSN: 1547-1063 Impact factor: 2.080