Literature DB >> 31499653

A theta-scheme approximation of basic reproduction number for an age-structured epidemic system in a finite horizon.

Wen Juan Guo1, Ming Ye2, Xi Ning Li1, Anke Meyer-Baese3, Qi Min Zhang1.   

Abstract

This paper focuses on numerical approximation of the basic reproduction number R0, which is the threshold defined by the spectral radius of the next-generation operator in epidemiology. Generally speaking, R0 cannot be explicitly calculated for most age-structured epidemic systems. In this paper, for a deterministic age-structured epidemic system and its stochastic version, we discretize a linear operator produced by the infective population with a theta scheme in a finite horizon, which transforms the abstract problem into the problem of solving the positive dominant eigenvalue of the next-generation matrix. This leads to a corresponding threshold R0,n . Using the spectral approximation theory, we obtain that R0,n → R0 as n → +∞. Some numerical simulations are provided to certify the theoretical results.

Keywords:  Numerical approximation; age-structure epidemic system; basic reproduction number; spectral radius; theta scheme

Mesh:

Year:  2019        PMID: 31499653     DOI: 10.3934/mbe.2019204

Source DB:  PubMed          Journal:  Math Biosci Eng        ISSN: 1547-1063            Impact factor:   2.080


  1 in total

1.  Collocation of Next-Generation Operators for Computing the Basic Reproduction Number of Structured Populations.

Authors:  Dimitri Breda; Toshikazu Kuniya; Jordi Ripoll; Rossana Vermiglio
Journal:  J Sci Comput       Date:  2020-10-31       Impact factor: 2.592

  1 in total

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