Literature DB >> 31497833

Recent advances in the synthesis of carbazoles from indoles.

Trapti Aggarwal1, Akhilesh K Verma1.   

Abstract

Carbazoles are privileged nitrogen heterocycles that are present in a wide range of natural products, pharmaceuticals, and functional materials. Due to their wide application, various synthetic strategies are available in the literature using substituted amines or indoles as a substrate. Thus, this review comprehensively highlights the (2015-2019) article that focuses on the synthesis of carbazoles derived from an indole-template through transition-metal catalyzed C-H functionalization, metal-free cyclization, three-component reaction, and electrophilic iodocyclizations. The synthetic strategies described in this review provided diversely substituted carbazoles and few of them have profound pharmacological activity.

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Year:  2019        PMID: 31497833     DOI: 10.1039/c9ob01381d

Source DB:  PubMed          Journal:  Org Biomol Chem        ISSN: 1477-0520            Impact factor:   3.876


  3 in total

1.  Synthesis of indoles, indolines, and carbazoles via palladium-catalyzed C─H activation.

Authors:  Alexander J Rago; Guangbin Dong
Journal:  Green Synth Catal       Date:  2021-03-04

2.  Synthesis of Carbazoles by a Diverted Bischler-Napieralski Cascade Reaction.

Authors:  Matteo Faltracco; Said Ortega-Rosales; Elwin Janssen; Răzvan C Cioc; Christophe M L Vande Velde; Eelco Ruijter
Journal:  Org Lett       Date:  2021-03-31       Impact factor: 6.005

3.  Synthesis of 4-Hydroxycarbazole Derivatives by Benzannulation of 3-Nitroindoles with Alkylidene Azlactones.

Authors:  Dongdong Cao; Gang Chen; Dingben Chen; Zhijun Xia; Zongyang Li; Yi Wang; Dongqing Xu; Jianguo Yang
Journal:  ACS Omega       Date:  2021-06-25
  3 in total

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