Literature DB >> 3149663

In vivo modulation of murine collagen induced arthritis.

G E Ranges1, S Fortin, M T Barger, S Sriram, S M Cooper.   

Abstract

The effects of in vivo modulation of murine collagen induced arthritis with monoclonal anti-CD4 antibodies, monoclonal anti-Ia antibodies, and gamma interferon are reviewed. We detail the mechanism of action of monoclonal anti-CD4 antibody on humoral and cell mediated immune responses and discuss the implications for designing therapeutic strategies. To further explore the induction of collagen induced arthritis, a syngeneic cell transfer system using collagen primed T lymphocytes is described. This cell transfer system provides an opportunity to study the role of CD4 positive T lymphocytes in arthritis induction during a short, defined time period.

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Year:  1988        PMID: 3149663     DOI: 10.3109/08830188809044772

Source DB:  PubMed          Journal:  Int Rev Immunol        ISSN: 0883-0185            Impact factor:   5.311


  5 in total

1.  In vivo elimination of T cells expressing specific T-cell receptor V beta chains in mice susceptible to collagen-induced arthritis.

Authors:  T J Goldschmidt; L Jansson; R Holmdahl
Journal:  Immunology       Date:  1990-04       Impact factor: 7.397

2.  Successful transfer of collagen-induced arthritis to severe combined immunodeficient (SCID) mice.

Authors:  R O Williams; C Plater-Zyberk; D G Williams; R N Maini
Journal:  Clin Exp Immunol       Date:  1992-06       Impact factor: 4.330

3.  Modulation of IL-17 and Foxp3 expression in the prevention of autoimmune arthritis in mice.

Authors:  Joana Duarte; Ana Agua-Doce; Vanessa G Oliveira; João Eurico Fonseca; Luis Graca
Journal:  PLoS One       Date:  2010-05-10       Impact factor: 3.240

4.  Cell-mediated transfer of collagen-induced arthritis in mice and its application to the analysis of the inhibitory effects of interferon-gamma and cyclophosphamide.

Authors:  H Nakajima; Y Hiyama; H Takamori; W Tsukada
Journal:  Clin Exp Immunol       Date:  1993-05       Impact factor: 4.330

5.  Role of IL-2 and IL-4 in exacerbations of murine antigen-induced arthritis.

Authors:  M J Jacobs; A E van den Hoek; P L van Lent; F A van de Loo; L B van de Putte; W B van den Berg
Journal:  Immunology       Date:  1994-11       Impact factor: 7.397

  5 in total

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